Protein sequences encompass tertiary structures and contain information about specific molecular interactions, which in turn determine biological functions of proteins. Knowledge about how protein sequences define interaction specificity is largely missing, in particular for paralogous protein families with high sequence similarity, such as the plant MADS domain transcription factor family. In ...

The purpose of this paper is to propose a model of risk analysis which combines two tools belonging to a different context. These both tools are MADS (Model of Analysis of Dysfunctional Systems) and UML (Unified Model Language). The proposed method aims to integrate UML language, especially the collaboration diagram, in the MADS model. We represent the danger source system of MADS model with th...

In Arabidopsis thaliana, the three MADS box genes SEEDSTICK (STK), SHATTERPROOF1 (SHP1), and SHP2 redundantly regulate ovule development. Protein interaction studies have shown that a multimeric complex composed of the ovule identity proteins together with the SEPALLATA MADS domain proteins is necessary to determine ovule identity. Despite the extensive knowledge that has become available about...

OBJECTIVES To assess the effectiveness of mandibular advancement devices (MADs) for the treatment of obstructive sleep apnea syndrome (OSAS) over a long-term follow-up in patients non-compliant with continuous positive airway pressure (CPAP) and to identify potential predictive factors of response to MADs. METHODS Fifteen OSAS patients were enrolled. Apnea-hypopnea index (AHI) and daytime sle...

Technologically speaking, humanity lives in an age of evolution, prosperity, and great development, as a new generation the Internet has emerged; it is Things (IoT) which controls all aspects lives, from different devices home to large industries. Despite tremendous benefits offered by IoT, still there are some challenges regarding privacy information security. The traditional techniques used M...

We propose magnetically arrested disks (MADs) in quiescent black-hole (BH) binaries as the origin of multiwavelength emission, and argue that this class sources can dominate cosmic-ray spectrum around knee. X-ray luminosities Galactic BH state are far below Eddington luminosity, thus, radiatively inefficient accretion flows (RIAFs) formed inner region. Strong thermal turbulent pressures RIAFs p...

In plants MADS-box transcription factors (TFs) play important roles in growth and development. However, no plant MADS-box gene has been identified to have a function related to secondary metabolites regulation. Here, a MADS-box TF gene, designated as HbMADS4, was isolated from Hevea brasiliensis by the yeast one-hybrid experiment to screen the latex cDNA library using the promoter of the gene e...

Phylogenomic analyses show that gene and genome duplication events have led to the diversification of transcription factor gene families throughout the evolutionary history of land plants and that gene duplications have played an important role in shaping regulatory networks influencing key phenotypic characters including floral development and flowering time. A molecular evolutionary investiga...

MADS-box genes encode transcriptional regulators that are critical for flowering, flower organogenesis and plant development. Although there are extensive reports on genes involved in flower organogenesis in model and economically important plant species, there are few reports on MADS-box genes in woody plants. In this study, we have cloned and characterized AGAMOUS (AG), SEEDSTICK (STK) and SE...

OsMADS29 is a seed-specific MADS-box transcription factor that affects embryo development and grain filling by maintaining hormone homeostasis and degradation of cells in the nucellus and nucellar projection. Although it has a bipartite nuclear localization signal (NLS) sequence, the transiently expressed OsMADS29 monomer does not localize specifically in the nucleus. Dimerization of the monome...