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Dynamic memory management requires special attention in programming. It should be fast and secure at the same time. This paper proposes a new randomized dynamic algorithm designed to meet these requirements. Randomization is key feature intended protect applications from "use-after-free" or similar attacks. At time, state consists only of one pointer, so it does not consume extra for itself. Ho...

Transpeptidase-catalyzed protein and peptide modifications have been widely utilized for generating conjugates of interest biological investigation or therapeutic applications. However, all known transpeptidases are constrained to ligating in the N-to-C orientation, limiting scope attainable products. Here, we report that an engineered asparaginyl ligase accepts diverse incoming nucleophile sub...