Chinese hamster and mouse sarcoma 180 ascites cells, treated with high levels of actinomycin D, still carry out limited poly(A) synthesis. The residual activity, which consists of poly(A) chain extension in the cytoplasm as well as in the nucleus, is essentially insensitive to cordycepin. Nuclear polyadenylation proceeds linearly and involves the gradual extension of unusually long poly(A) sequ...

The chromosomal constitutions of four amethopterin-resistant sublines of cultured Sarcoma 180 cells were compared with those of two sensitive sublines. No correlation between amethopterin resistance and chromosomes was observed. The chromosomal character of a resistant subline was completely retained in the sensitive subline derived from it after 9 months of continuous cultivation in the absenc...

Pearson, J. S. &Wood, E. J. (1974) Biochem. SOC. Trans. 2, 333-336 Poulik, M. D. (1957) Nature (London) 180, 1477-1479 VanBreernen, J. F. L.,Schuurhuis,G. J. &Van Bruggen,E. F. J. (1977) in StructureandFunction of Haemocyanin (Bannister, J. V., ed.), pp. 122-127, Springer-Verlag, Berlin and Heidelberg Weber, K. & Osborn, M. (1969) J. Biol. Chem. 244,4406-4412 Wood, E. J. (1973) Biochim. Biophys...

Negative results are reported for five compounds tested against mouse Sarcoma 180. Twelve mice, 18 gm. Rockland and Carworth Farms mice, were used for each test. The tumors were implanted subcutaneously by trocar in the right axilla. When the implants were seven days old the compounds were in jected intraperitoneallytwice a day for seven days. The compounds were tested at the maximum non-lethal...

The effects of dietary-induced acidosis on the growth and rates of complete regression of Sarcoma 180 in mice have been studied. The experiments here reported have demonstrated that mineral acidification of laboratory food produces a late decrease in tumor growth and significantly increases the rates of complete tumor regression. Blood acid-base studies also demonstrate the effects of these die...

The growth rate of Sarcoma 180 and of a mammary adenocarcinoma in potassium deficient mice did not significantly differ from that in pair-fed control mice. The po tassium concentration of these tumors in potassium-deficient mice was the same as in the control mice, although the potassium concentration of muscle and plasma was only half of that in the controls. The in vivo equilibration of K@ in...

One of the problems sustainable agricultural land management (SALM) is competition between food production and biomass production. For this reason, marginal lands with unfavorable agrotechnical conditions have been proposed for non-food crops in recent years. To end, a better understanding impact environmental factors on crop development yield needed. The objective study was to investigate effe...