The Amirkabir petrochemical complex (APC) is located in the south of Iran, on the northern coastline of the Persian Gulf. It has five different units which generate various waste estimated at 3115.98 ton/year. The objective of this study was to focus on the management of the processing wastes for minimizing the adverse environmental impacts. In order to properly manage and control waste generat...

Background/Aim. Direct oral anticoagulants (DOACs) administration significantly interferes with coagulation as-says. The aim of the study was to evaluate effect DOACs and DOAC-Remove? on assays during thrombophilia testing. Methods. carried out from January 2019 end June 2020. It included 30 DOAC-treated patients, 14 females 16 males aged 23 63 (median age 47.6 years), tested for due venous thr...

Changes in mitochondrial bioenergetics have been proposed to be critical for triggering and effecting anesthetic-induced preconditioning (APC) against cardiac ischemia and reperfusion injury. The objective of this study was to analyze changes in mitochondrial protein levels and link those changes to potential functional changes. A (18)O-labeling method was applied for relative comparison of car...

The anaphase-promoting complex/cyclosome (APC/C) is a large multimeric cullin-RING E3 ubiquitin ligase that orchestrates cell-cycle progression by targeting cell-cycle regulatory proteins for destruction via the ubiquitin proteasome system. The APC/C assembly comprises two scaffolding subcomplexes: the platform and the TPR lobe that together coordinate the juxtaposition of the catalytic and sub...

The Open Access (OA) publishing model that is based on article processing charges (APC) often associated with the potential for more transparency regarding expenditures publications. However, extent to which can be achieved depends not least completeness of data in APC monitoring systems. This investigates two blind spots largest collection payment information, OpenAPC. It aims identify likely ...

Truncation mutations in the adenomatous polyposis coli protein (APC) are responsible for familial polyposis, a form of inherited colon cancer. In addition to its role in mediating beta-catenin degradation in the Wnt signaling pathway, APC plays a role in regulating microtubules. This was suggested by its localization to the end of dynamic microtubules in actively migrating areas of cells and by...

The tumor suppressor protein adenomatous polyposis coli (APC) regulates cell protrusion and cell migration, processes that require the coordinated regulation of actin and microtubule dynamics. APC localizes in vivo to microtubule plus ends and actin-rich cortical protrusions, and has well-documented direct effects on microtubule dynamics. However, its potential effects on actin dynamics have re...

Inactivation of the adenomatous polyposis coli (APC) gene is a major initiating event in colorectal tumorigenesis. Most of the mutations in APC generate premature stop codons leading to truncated proteins that have lost beta-catenin binding sites. APC-free beta-catenin stimulates the Wnt signaling pathway, leading to active transcription of target genes. In the current study, we describe a nove...