It has been reported that the water extract of the whole unripe fruit of Momordica charantia can significantly reduce blood glucose levels. However the safety of its use during pregnancy has not been fully investigated. The aim of this investigation is to determine the safety of this extract during pregnancy. The water extract of the unripe fruit was given to pregnant Sprague Dawley rats on day...

Bitter gourd (Momordica charantia), a commonly consumed vegetable is used as an adjunct in the management of diabetes mellitus. A study was carried out to examine the effect of edible portion of bitter gourd at 10% level in the diet in streptozotocin induced diabetic rats. To evaluate the glycaemic control of bitter gourd during diabetes, diet intake, gain in body weight, water intake, urine su...

Pare (Momordica charantia L.) adalah suatu tanaman yang tumbuh didaerah tropis yaitu daerah Asia, Amazon (Amerika Selatan), Afrika Timur dan Karibia. Rasa pahit buah ini menimbulkan beberapa manfaat diantaranya merangsang nafsu makan, menyembuhkan penyakit kuning, melancarkan pencernaan. pada pare disebabkan oleh kandungan momordikosida golongan glukosida triterpen atau kukurtibasin. Penelitian...

Objective: The present study was conducted to determine the hypoglycemic and antioxidant potential of polyherbal formulation in alloxan induced diabetic rats. Study Design: In five different groups an aqueous suspension of herbal mixture containing equal amounts of– Azadirachta indica, Gymnema sylvestre, Momordica charantia, Syzigium cumini, Trigonella foenum was administered orally once a day ...

Bitter melon is a fruit that was famous for its bitter taste and contains chemical compounds are proven to have effects such as antidiabetic, anti-inflammatory, antipyretic, antioxidant. One of the prerequisites plant be developed into drug by testing subchronic toxicity. This study goal determine presence toxic not detected in acute toxicity test. A total 40 wistar rats were divided group cont...

Diabetes mellitus (DM) is the most common of the endocrine disorders and represents a global health problem. DM is characterized by chronic hyperglycaemia due to relative or absolute lack of insulin or the actions of insulin. Insulin is the main treatment for patients with type 1 DM and it is also important in type 2 DM when blood glucose levels cannot be controlled by diet, weight loss, exerci...