The genetic analysis of the Rubinstein-Taybi syndrome (RTS, OMIM 180849) may shed light on mechanisms of transcription, brain function, keloid formation, and cancer. RTS can be caused by heteroallelic mutations of CREBBP (the gene for cAMP responsive element binding (CREB) binding protein). Human CREBBP resides on chromosome 16p13.3, spans approximately 150 kb at the genomic level, and comprise...

The malaria vaccine candidate, RTS,S/AS01(E), showed promising protective efficacy in a trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the vaccine's safety and tolerability. The experimental design was a Phase 2b, two-centre, double-blind (observer- and participant-blind), randomised (1∶1 ratio) controlled trial. Three doses of study or control (rabies) vaccines w...

BACKGROUND Our purpose was to compare the Revised Trauma Score (RTS) with the new Field Triage Score (FTS) for prediction of mortality (MORT) and of need for massive transfusion (MASS, >or=10 units of packed cells or whole blood) in casualties arriving at combat support hospitals in Iraq. METHODS Six hundred ninety-two cases were reviewed; 536 had complete data and were included. Total Glasgo...

This study aimed to investigate the acute effects of passive static and ballistic stretching on maximal repetition performance during a resistance training session (RTS). Nine male subjects underwent three experimental conditions: ballistic stretching (BS); passive static stretching (PSS); and a specific warm-up (SW). The RTS was composed of three sets of 12RM for the following exercises: leg p...

BACKGROUND Respiratory therapist (RT) is a nascent career in China, so little information is available about intensive care unit (ICU) respiratory care resources and practices, requirements for RTs, and barriers to recruit RTs. METHODS Using survey methodology, we designed and mailed a questionnaire to ICU supervisors and staffs at all 106 ICUs within 46 tertiary and university-affiliated ho...

BACKGROUND Knee osteotomies are proven treatment options, especially in younger patients with unicompartmental knee osteoarthritis, for certain cases of chronic knee instability, or as concomitant treatment for meniscal repair or transplantation surgery. Presumably, these patients wish to stay active. Data on whether these patients return to sport (RTS) activities and return to work (RTW) are s...

PURPOSE Pulmonary rehabilitation (PR) is recognized as the chief non-pharmacologic management approach for patients with COPD, but is clinically under-utilized. In Taiwan, respiratory therapists (RTs) are one of the first-line health care providers who spend vast amounts of time with COPD patients in PR programs. To better enhance patients' knowledge of and participation in PR, it is necessary ...

We report two unusual patients with Rothmund-Thomson syndrome (RTS), a rare genodermatosis. The first patient is a 5-year-old girl with congenital poikiloderma, photosensitivity, plantar punctate keratoderma, stunted growth and severe mental retardation. Plantar keratoderma associated with RTS has been reported only once. The second patient is a 21-year-old female presenting with rounded "moon"...

Most of the tasks in wireless sensor networks (WSN) are requested to run in a real-time way. Neither EDF nor FIFO can ensure real-time scheduling in WSN. A real-time scheduling strategy (RTS) is proposed in this paper. All tasks are divided into two layers and endued diverse priorities. RTS utilizes a preemptive way to ensure hard real-time scheduling. The experimental results indicate that RTS...

We report reaction temperature sensing (RTS)-based control to fundamentally enhance Li-ion battery safety. RTS placed at the electrochemical interface inside a Li-ion cell is shown to detect temperature rise much faster and more accurately than external measurement of cell surface temperature. We demonstrate, for the first time, that RTS-based control shuts down a dangerous short-circuit event ...