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We report the discovery of a quasar at z = 3.050 ± 0.003, closely coincident in redshift with the isolated low-opacity feature seen near z 3.056 in the otherwise black portion of the He Gunn-Peterson absorption trough seen toward the z = 3.286 background quasar Q0302−003, located 6. 5 away on the sky. We explore plausible models for the He ionization zone created by this neighboring quas...
Cardiac troponin (cTn) is a key biomarker for the assessment of myocardial injury, but overutilization of this test has increased workload and costs. We developed and implemented an algorithm to eliminate excessive utilization. Significant reduction was observed after the implementation of the algorithm in total cTnI requests (29.9%; P = .007), requests from outpatient clinics (70.7%; P = .003)...
BACKGROUND Local anesthetics are an important component of perioperative pain management, but the duration of action of available products is limited. We hypothesized that a single local infiltration of a novel bupivacaine liposome injectable suspension (AT-003) would provide clinically effective analgesia over a 72-h period. In a masked, randomized, placebo-controlled, multi-center pilot field...
The mechanism by which magnesium therapy suppresses some ventricular tachyarrhythmias characterized by a prolonged QT interval (e.g., torsades de pointes) is unknown. Since early afterdepolarizations have been proposed as a cause of the long QT syndrome and the related ventricular tachyarrhythmias, we hypothesized that magnesium therapy would suppress both the early afterdepolarizations and the...
There are many applications which arise in telecommunications information processing in which it is useful, and often necessary, to create and access multiple hypothetical states. These might correspond to future states reeecting pending updates (such as customer service orders), or hypothetical alternative states that would arise in the exploration of diierent solutions to a given problem. In ...
The aim of this study is to determine the nutrition and physical activity habits university students examine relationship between body mass index (BMI) academic achievement these habits. This descriptive cross-sectional was conducted with 127 second-year at a university. A questionnaire consisting multiple choice questions used in study. data were analyzed using SPSS (Statistical Package for So...
Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe thrombocytopenia. Here, we review the literature on viral hemorrhagic fever and discuss the role played by platelets in the coagulopathy. We also discuss the...
Filovirus infections can cause a severe and often fatal disease in humans and nonhuman primates, including great apes. Here, three anti-Ebola virus mouse/human chimeric mAbs (c13C6, h-13F6, and c6D8) were produced in Chinese hamster ovary and in whole plant (Nicotiana benthamiana) cells. In pilot experiments testing a mixture of the three mAbs (MB-003), we found that MB-003 produced in both man...
UNLABELLED BACKGROUND In addition to stimulating linear growth in children, growth hormone (GH) influences metabolism and body composition. These effects should be considered when individualizing GH treatment as dose-dependent changes in metabolic markers have been reported. HYPOTHESIS There are different dose-dependent thresholds for metabolic effects in response to GH treatment. METHOD...
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