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Papanicolaou smears have false-negative rates of 6 percent to 56 percent that are due, in large part, to inadequate sampling of endocervical cells. A randomized, prospective trial was conducted comparing the adequacy of Papanicolaou smears obtained with the cytobrush and Ayre spatula with smears obtained with the extended-tip spatula, as measured by the presence of endocervical cells. One hundr...
14-3-3 proteins play a pivotal role in controlling cell proliferation and survival, two commonly dysregulated hallmarks of cancers. 14-3-3 protein expression is enhanced in many human cancers and correlates with more aggressive tumors and poor prognosis, suggesting a role for 14-3-3 proteins in tumorigenesis and/or progression. We showed previously that the dimeric state of 14-3-3 proteins is r...
acute infectious gastroenteritis is one of the most common infectious diseases of humans in the world. diarrheal disease still ranks very high as a major cause of illness and death especially in developing nations. this study has been carried out to investigate enteropathogenic bacteria isolated from 2517 specimens of patients with diarrhea. the results obtained are as follow: salmonella typhim...
BACKGROUND Cancer treatment efficacy has improved with therapies at high or sustained dosages. However, there is increasing concern about symptom management and patients' quality of life. OBJECTIVE The objective of this study was to assess whether use of a Therapy-Related Symptom Checklist (TRSC) with oncology outpatients increases the number of symptoms documented and managed and whether thi...
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