نتایج جستجو برای: 1 although vcam

تعداد نتایج: 3214491  

Journal: :European review for medical and pharmacological sciences 2015
Y Jiang L-L I Jiang X-M Z Y Maimaitirexiati Y Zhang L Wu

OBJECTIVE It is widely recognized that atherosclerosis is a chronic inflammatory disease. Intracellular adhesion molecule-1 (ICAM-1), vascular cellular adhesion molecule-1 (VCAM-1), and E-selectin play vital roles in inflammatory processes. ICAM-1, VCAM-1, and E-selectin expression is regulated by nuclear factor (NF)-κB signaling. It has been reported that irbesartan can decrease expression of ...

Journal: :Circulation 2008
Carolyn Z Behm Beat A Kaufmann Chad Carr Miles Lankford John M Sanders C Edward Rose Sanjiv Kaul Jonathan R Lindner

BACKGROUND Inflammatory responses contribute to vascular remodeling during tissue repair or ischemia. We hypothesized that inflammatory cell recruitment and endothelial cell activation during vasculogenesis and ischemia-mediated arteriogenesis could be temporally assessed by noninvasive molecular imaging. METHODS AND RESULTS Contrast ultrasound perfusion imaging and molecular imaging with mic...

Journal: :Acta Histochemica et Cytochemica 2008
Kana Iwasawa Takeshi Kameyama Hiroyuki Ishikawa Yoshihiko Sawa

This study investigated the TNF-alpha-induced ICAM-1 and VCAM-1 expression on mouse lingual lymphatic vessels. All podoplanin-positive lymphatic vessels expressed PECAM-1. In the lamina propria mucosae of TNF-alpha-treated tongue, almost all initial lymphatics expressed ICAM-1. There were initial lymphatics with the VCAM-1 expression and also the vessels without the expression. In the tunica mu...

Journal: :The Journal of clinical investigation 1995
B V Khan S S Parthasarathy R W Alexander R M Medford

Early features in the pathogenesis of atherosclerosis include accumulation of oxidized LDL (oxLDL) and endothelial expression of the vascular adhesion molecule VCAM-1. Because antioxidants inhibit endothelial VCAM-1 expression, we tested the hypothesis that oxLDL functions as a prooxidant signal in atherogenesis to augment VCAM-1 activation by inflammatory signals. Cultured human aortic endothe...

Journal: :Diagnostics 2021

Immunological explanatory approaches are becoming increasingly important in schizophrenia research. In this context, the function of blood-brain barrier (BBB) and blood-cerebrospinal fluid (CSF) (BCSFB) plays an essential role. Different adhesion molecules, such as intercellular molecule-1 (ICAM-1) vascular cell (VCAM-1), key elements sustaining integrity BBB BCSFB. The objectives study were to...

Journal: :Complementary Therapies in Medicine 2021

• The overall effect revealed taking soy protein plus isoflavones could not reduce serum concentration of studied CAMs. Soy E-selectin in studies with sample size <84. VCAM-1 which participants’ age is ?55 years old. combination might the inflammatory mediators. In this study, we attempted to summarize combined on circulating E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular ...

Journal: :Circulation research 2000
Y Huo A Hafezi-Moghadam K Ley

Atherosclerotic lesion development seems to be inflammatory in nature and involves the recruitment of monocytes to the vessel wall. In this study, we investigated the role of vascular cell adhesion molecule-1 (VCAM-1) and fibronectin (FN) connecting segment-1 containing the amino acid sequence ILDV as functional ligands for alpha(4)beta(1) integrin (VLA-4) in monocyte rolling and adherence to e...

Journal: :Thrombosis and haemostasis 2008
Leigh A Madden Rebecca V Vince Marie E Sandström Lee Taylor Lars McNaughton Gerard Laden

An increased risk of death or severe injury due to late-morning thrombotic events is well established. Tissue factor (TF) is the initiator of the coagulation cascade, and endothelial stresses, coupled with production of pro-coagulant microparticles (MP) are also important factors in loss of haemostasis. TF and vascular cell adhesion molecule-1 (VCAM-1) -positive cell microparticles were assesse...

2017
Xiaosa Li Weiyu Chen Ping Li Jinzhi Wei Yang Cheng Pei Liu Qing Yan Xingyan Xu Yuhong Cui Zhengtian Gu Tommaso Simoncini Xiaodong Fu

Rationale: Postmenopausal atherosclerosis (AS) has for decades been attributed to estrogen deficiency. Although the follicular stimulating hormone (FSH) levels rise sharply in parallel, the direct effect of FSH on AS has never been investigated. In this study, we explored the possible role of FSH in the development of AS. Methods: This was a prospective cohort study of 48 healthy premenopausal ...

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