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Interactions between disseminated tumor cells (DTC) and stromal cells in the microenvironment are critical for tumor colonization of distal organs. Recent studies have shown that vascular cell adhesion molecule-1 (VCAM-1) is aberrantly expressed in breast cancer cells and mediates prometastatic tumorstromal interactions.Moreover, the usefulness of VCAM-1 toDTCs in 2different organs—lung andbone...

We examined the mechanisms used by eosinophils to tether and accumulate on interleukin-4 (IL-4)–stimulated human umbilical vein endothelial cells (HUVECs) under flow conditions. As previously reported, HUVECs treated for 24 hours with 20 ng/mL IL-4 had increased expression of P-selectin and vascular cell adhesion molecule-1 (VCAM-1) but not E-selectin. We found that eosinophils tethered and rol...

A natural way to describe the Penrose tiling employs the projection method on the basis of the root lattice A4 or its dual. Properties of these lattices are thus related to properties of the Penrose tiling. Moreover, the root lattice A4 appears in various other contexts such as sphere packings, efficient coding schemes and lattice quantizers. Here, the lattice A4 is considered within the icosia...

BACKGROUND We aimed to test the hypothesis that the correlation of the changes in the blood Androstenedione (A4) levels to the number of selected follicles during ovulation induction with low-dose recombinant human follicle stimulating hormone (rhFSH) is as strong as the correlation to changes in the blood Estradiol (E2) levels in polycystic ovary syndrome (PCOS). METHODS Prospective Case-con...

We show that there are only finitely many Diophantine quadruples, that is, sets of four positive integers {a1, a2, a3, a4} such that aiaj +1 is a square for all 1 ≤ i < j ≤ 4, consisting of Fibonacci numbers.

A Lie theoretic interpretation is given to a pattern with five-fold symmetry occurring in aperiodic Penrose tiling based on isosceles triangles with length ratios equal to the Golden Section. Specifically a B(∞) crystal based on that of Kashiwara is constructed exhibiting this five-fold symmetry. It is shown that it can be represented as a Kashiwara B(∞) crystal in type A4. Similar crystals wit...

The application of fuzzy time series is used to view the stock clothing materials. As for problem so far, CV Duta Express does not have a model seeing complete materials in warehouse, process optimal. This will an impact on orders that come at same and large quantities. avoid shortages, which resulted company experiencing losses. purpose this study make it easier predict be able analyze every m...

Class 3 semaphorins are anti-angiogenic and anti-tumorigenic guidance factors that bind to neuropilins, which, in turn, associate with class A plexins to transduce semaphorin signals. To study the role of the plexin-A2 receptor in semaphorin signaling, we silenced its expression in endothelial cells and in glioblastoma cells. The silencing did not affect Sema3A signaling, which depended on neur...