Alman İmparatoru Friedrich Barbarossa’nın hizmetinde Burchard von Strazburg 1175 yılında diplomatik bir görevle Mısır’a seyahat etti. Burchard’ın görevi daha önce Barbarossa ile Sultan Selahâddîn Eyyûbî arasında yapılan siyasi ve ticari antlaşmaları uzatmak bölge hakkında bilgi toplamaktı. elçi İskenderiye’ye vardığında Şam’da bulunuyordu. Burchard, sultanla görüşmek üzere kara yoluyla Suriye’y...

New therapeutic strategies are necessary to improve the treatment of lung cancer. We investigated the effects of bombesin/gastrin-releasing peptide (GRP) antagonist, RC-3940-II, and growth hormone-releasing hormone (GHRH) antagonists, MZ-J-7-114 and MZ-J-7-118, on the expression of epidermal growth factor receptor (EGFR)/HER (-2, -3, and -4) family, angiogenic factors, VEGF-A and VEGF receptors...

Three years have passed since the BELLE discovery of the X(3872), and there are still (at least) two competing interpretations of this particle, which resembles a charmonium but behaves in a dramatic different way from it. Is X a molecule of two D mesons or a compact four-quark state? Are these two pictures really resolvable? The quantum mechanical intuition can also lead to more refined pictur...

The auditory sensory end organ is under the control of the central nervous system via efferent projections. Contralateral suppression of otoacoustic emissions (acoustic signatures of the cochlear biomechanical activity) provides a non-invasive approach to assess olivocochlear efferent activity in humans. Using this approach, the present study compared professional musicians with musically-inexp...

Here we examine hypothesis that short-term peripheral ZnSO4-induced anosmia can produce effects on c-fos expression within spinal cord and caudal medulla in male Wistar rats (n ˆ 4). Fos-like-immunoreactive cells revealed by avidinbiotin-peroxidase method show a signi®cant bilateral increase in the nucleus proprius (layers 3 and 4) and medial part of layers 5 and 6. In substantia gelatinosa (la...

While psychopaths (PP) lack anticipatory fear, social phobics (SP) are characterized by excessive fear. Criminal PP, SP and healthy controls (HC) participated in differential aversive delay conditioning with neutral faces as conditioned (CS) and painful pressure as unconditioned stimuli. Functional magnetic resonance imaging revealed differential activation in the limbic–prefrontal circuit (orb...

Serotonin (5-HT) has been shown to in ̄uence the development of the rodent barrel ®eld by affecting the patterning of thalamic axons in the somatic sensory cortex. To determine whether this is a direct effect on thalamocortical neurones, we analyzed primary thalamic cultures taken from E15 mouse embryos. We show that 5-HT enhances neurite outgrowth of thalamic neurones. The sodium channel blocke...

A multitude of tasks that we perform on a daily basis require precise information about the orientation of our limbs with respect to the environment and the objects located within it. Recent studies have suggested that the inertia tensor, a physical property whose values are timeand co-ordinate-independent, may be an important informational invariant used by the proprioceptive system to control...