نتایج جستجو برای: 123 metaiodobenzylguanidine

تعداد نتایج: 18791  

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010
David J Brooks

Parkinson disease (PD) is associated with nigral degeneration and striatal dopamine deficiency. Demonstrating midbrain structural abnormalities with transcranial sonography or diffusion-weighted MRI or showing striatal dopamine terminal dysfunction with PET or SPECT supports the diagnosis and rationalizes the use of dopaminergic medications. In atypical PD variants, transcranial sonography can ...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011
Nikolaos D Papathanasiou Mark N Gaze Kevin Sullivan Matthew Aldridge Wendy Waddington Ahmad Almuhaideb Jamshed B Bomanji

UNLABELLED The aim of our study was to evaluate prospectively the diagnostic performance and prognostic significance of (18)F-FDG PET/CT in comparison with (123)I-metaiodobenzylguanidine ((123)I-MIBG) imaging in patients with high-risk neuroblastoma. METHODS Twenty-eight patients with refractory or relapsed high-risk neuroblastoma (16 male and 12 female patients; age range, 2-45 y; median age...

2010
Kenichi Nakajima Shinro Matsuo Minoru Hasegawa Seigo Kinuya Kazuhiko Takehara

Myocardial involvement is an important prognostic factor in patients with systemic sclerosis, and early diagnosis and staging of the disease have been sought after. Since myocardial damage is characterized by connective tissue disease, including fibrosis and diffuse vascular lesions or microcirculation, nuclear myocardial perfusion imaging has been a promising option for evaluating myocardial d...

Objective(s): Iodine-123 metaiodobenzylguanidine (123I-MIBG) myocardial scintigraphy has been used to evaluate cardiac sympathetic denervation in Lewy body disease (LBD), including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). The heart-tomediastinum ratio (H/M) in PD and DLB is significantly lower than that in Parkinson’s plus syndromes and Alzheimer’s disease. Although this ra...

2005
Shinro Matsuo Shinro MATSUO Ichiro NAKAE Daisuke MASUDA Tetsuya MATSUMOTO Minoru HORIE

PLASMA NOREPINEPHRINE CONCENTRATIONS, which increase in patients with congestive heart failure, reflect the severity of the disease and are closely related to prognosis.1 Because sympathetic activity is enhanced with increasing severity of congestive heart failure, the severity and prognosis of congestive heart failure can be evaluated based on parameters determined by I-123 metaiodobenzylguani...

2012
Steven G. DuBois Ethan Geier Vandana Batra Sook Wah Yee John Neuhaus Mark Segal Daniel Martinez Bruce Pawel Greg Yanik Arlene Naranjo Wendy B. London Susan Kreissman David Baker Edward Attiyeh Michael D. Hogarty John M. Maris Kathleen Giacomini Katherine K. Matthay

Purpose. (123)I-metaiodobenzylguanidine (MIBG) is used for the diagnostic evaluation of neuroblastoma. We evaluated the relationship between norepinephrine transporter (NET) expression and clinical MIBG uptake. Methods. Quantitative reverse transcription PCR (N = 82) and immunohistochemistry (IHC; N = 61) were performed for neuroblastoma NET mRNA and protein expression and correlated with MIBG ...

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