The human von Hippel-Lindau disease (VHL) gene has recently been identified and, based on the nucleotide sequence of a partial cDNA clone, has been predicted to encode a novel protein with as yet unknown functions [F. Latif et al., Science (Washington DC), 260: 1317-1320, 1993]. The length of the encoded protein and the characteristics of the cellular expressed protein are as yet unclear. Here ...

The purpose of this study was to establish normal thyroglobulin (Tg) reference intervals (RIs) in regions with adequate and more than adequate iodine intake according to the National Academy of Clinical Biochemistry (NACB) guidelines and to investigate the relationships between Tg and other factors.A total of 1317 thyroid disease-free adult subjects (578 men, 739 nonpregnant women) from 2 citie...

The functional expression of cloned Drosophila melanogaster and house fly (Musca domestica) voltage-sensitive sodium channels in Xenopus oocytes is enhanced, and the inactivation kinetics of the expressed channels are accelerated, by coexpression with the tipE protein, a putative sodium channel auxiliary subunit encoded by the tipE gene of D. melanogaster. These results predict the existence of...

Carbon black is manufactured by the vapour phase pyrolysis of heavy aromatic hydrocarbon feedstocks. Its manufacture is worldwide and the majority of its production is for use in the rubber industry especially tyre manufacture. Its carbonaceous nature has led many to investigate the occurrence of exposure-related medical conditions. To quantify any such relationships, it is necessary to assess ...

SETTING Tuberculosis (TB) is highly prevalent in prisons of the former Soviet Union. OBJECTIVE To understand the behavioral, demographic and biological factors placing inmates in Tajikistan at risk for active TB. DESIGN We administered a behavioral and demographic survey to 1317 inmates in two prison facilities in Sughd province, Tajikistan along with radiographic screening for pulmonary TB...

AIMS To investigate the consequences of improvement in the workplace environment over six decades (1940-96) in asbestos miners and millers from a developing country (Brazil). METHODS A total of 3634 Brazilian workers with at least one year of exposure completed a respiratory symptoms questionnaire, chest radiography, and a spirometric evaluation. The study population was separated into three ...

OBJECTIVE This study assessed the correlation between compliance with set performance standards and maternal and neonatal deaths in health facilities. DESIGN Baseline and three annual follow-up assessments were conducted, and each was followed by a quality improvement initiative using the Standards Based Management and Recognition (SBM-R) approach. SETTING Twenty-three secondary health faci...

BACKGROUND/PURPOSE In a number of patients with acute myocardial infarction (AMI), myocardial hypoperfusion, known as the no-reflow phenomenon, persists after primary percutaneous intervention (PPCI). The aim of this study was to evaluate the feasibility and safety of a new quantitative method of measuring absolute blood flow and resistance within the perfusion bed of an infarct-related artery....

[2] Mostbeck, GH et al, J Comput Assist Tomogr. 1993,17:245-52 [3] Sagawa, K et al, Circulation 1981, 63:1223-1227 [4] Marsh, JD et al, Am J Cardiol. 1979, 44:1311-1317 Figure 2. Bland-Altman analysis of agreement for CO correlations (a) PC-MRI vs. P-V loops, (b) MRI cine vs. P-V loops. The difference is plotted as a function of the average of the result from two methods. The lines in the graph...

INTRODUCTION Despite the increasingly broad use of intraoperative neuromonitoring, review of the literature and clinical experience confirms there is little uniformity in application of and results across different centers. The aim of this study was to evaluate the ability of intraoperative neuromonitoring with a standardized evaluation of the signals to predict the postoperative functional out...