Visceral adiposity is strongly associated with metabolic disease risk, whereas subcutaneous adiposity is comparatively benign. However, their relative physiological importance in energy homeostasis remains unclear. Here, we show that after 24-h fasting, the subcutaneous adipose tissue of mice acquires key properties of visceral fat. During this fast-induced 'visceralization', upregulation of mi...

High-fat diet (HFD) plays a central role in the initiation of mitochondrial dysfunction that significantly contributes to skeletal muscle metabolic disorders in obesity. However, the mechanism by which HFD weakens skeletal muscle metabolism by altering mitochondrial function and biogenesis is unknown. Given the emerging roles of microRNAs (miRNAs) in the regulation of skeletal muscle metabolism...

Hepatocellular carcinoma (HCC) is one of the most common lethal malignancies in the world, and the current knowledge on the molecular and genetic basis of HCC is still limited. Previous study has shown miR-149 plays a tumor suppressive role in HCC, here we aimed to investigate the association between rs71428439 polymorphism, which located in the pre-miR-149, and the risk of HCC in a Chinese Han...

UNLABELLED Terbium offers 4 clinically interesting radioisotopes with complementary physical decay characteristics: (149)Tb, (152)Tb, (155)Tb, and (161)Tb. The identical chemical characteristics of these radioisotopes allow the preparation of radiopharmaceuticals with identical pharmacokinetics useful for PET ((152)Tb) and SPECT diagnosis ((155)Tb) and for α- ((149)Tb) and β(-)-particle ((161)T...

Mycoplasma genitalium was detected in 21 (14.1%) of 149 vaginal swab samples and in 1 (0.7%) of 149 throat washing samples from female sex workers during 2013-2014 in Japan. Prevalences of M. genitalium with macrolide resistance-associated 23S rRNA mutations and fluoroquinolone resistance-associated parC alterations were 47.1% and 36.8%, respectively.

Key Laboratory of Advanced Display and System Applications & SMIT Center, School of Automation and Mechanical Engineering, Shanghai University, No. 149 Yanchang Road, Shanghai 200072, P. R. China SMIT Center & Bionano Systems Laboratory, Department of Microtechnology and Nanoscience, Chalmers University of Technology, SE-412 96 Goteborg, Sweden School of Materials Science and Engineering, Shang...

III. EVENT STUDIES ......................................................................................................................... 138 A. Methodology .............................................................................................................. 138 B. Identifying the Announcement Day (Event Window) ................................................ 140 C. Measuring Retur...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate post-transcriptional gene expression via binding to the 3'-untranslated region (3'-UTR) of targeted mRNAs. They are reported to play important roles in tumorigenesis and progression of various cancers. Among them, miR-149 was confirmed to be aberrantly regulated in various tumors. In this review, we provide a complex overview of miR-149,...

We propose a novel method to classify alcohol abusers. The method efficiently estimates total power in gamma band frequency (GBF) of multi-channel Visual Evoked Potential (VEP) signals in the time domain, circumventing power spectrum computation. These are used as features to classify alcohol abusers from control subjects with Multilayer PerceptronBackpropagation (MLP-BP) and Fuzzy ARTMAP (FA) ...

Angel Rubio‡ University of the Basque Country UPV/EHU, Nano-Bio Spectroscopy Group, Avenida de Tolosa 72, 20018 San Sebastian, Spain and Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany. Center for Free-Electron Laser Science and Department of Physics, University of Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany (Dated: September...