In the crystal structure of the title compound, C(8)H(10)N(2)O(3), mol-ecules are linked by N-H⋯O hydrogen bonds, forming ribbons of centrosymmetric dimers extending along the c axis.

The title achiral compound, C(13)H(18)N(2)O, crystallized in the chiral monoclinic space group P2(1). The pyrrole rings are inclined to one another by 62.30 (11)°, and the propanol chain is in an extended conformation. In the crystal, the two pyrrole NH groups are involved in inter-molecular N-H⋯O hydrogen bonds, leading to the formation of a helical arrangement propagating along the b axis. An...

In the title compound, C9H10N2, the two pyrrole ring planes are twisted by a dihedral angle of 69.07 (16)° and the C-C-C methane angle is 115.1 (2)°. In the crystal, mol-ecules are connected into layers in the bc plane by N-H⋯π inter-actions.

In our previous studies we showed antitumor and anti-inflammatory activities of protein kinases inhibitor pyrrol derivate 1-(4-Cl-benzyl)-3-Cl-4-(CF3-fenylamino)-1H-pyrrol-2,5-dione (MI-1) on rat colon cancer model. Therefore anti-inflammatory effect of MI-1 on rat acetic acid induced ulcerative colitis (UC) model was aimed to be discovered. The anti-inflammatory effects of MI-1 (2.7 mg/kg dail...