A 33-year-old premenopausal multiparous woman with the history of septate uterus was referred to the hospital with menorrhagia and inter-menstrual bleeding occurring for the last 6 months. Work-up revealed a stage IIB cervical cancer. The patient underwent curative chemo/radiotherapy. The patient's septate uterus presented several difficulties during application. Brachytherapy was applied using...

Introduction: 192Ir is one of the important sources frequently used in brachytherapy. Up to now, a lot of commercial models of this source have been made which Ir-192 has been recently added to them. The aim of the present study is to determine the dosimetric parameters of this new source model based on the recommendations of TG-43(U1) protocol using Monte Carlo simulation tech...

Introduction: Passage of ionizing radiation through the organs of living creatures develops clusters of damaged nucleotides inside the DNA rounds. 192Ir Gamma source is one of the most widely used sources in brachytherapy of cervical and prostate cancer. Thus, in this research, we investigated the flux of photons and its resulting secondary electrons, the single-strand break (S...

The first quality assurance process for validating dose-volume histogram data involving brachytherapy procedures in radiation therapy is presented. The process is demonstrated using both low dose-rate and high dose-rate radionuclide sources. A rectangular cuboid was contoured in five commercially available brachytherapy treatment planning systems. A single radioactive source commissioned for QA...

Purpose: To evaluate the radiation attenuation properties of PC-ISO, a bio-compatible, sterilizable 3D printing material and its suitability for customized gynecologic (GYN) brachytherapy 15 applicators. Method: A custom radiochromic film dosimetry apparatus was 3D-printed in PC-ISO. The apparatus contained a single catheter channel and a slit to hold a radiochromic segment. A brachytherapy dos...

Brachytherapy using removable episcleral plaques containing sealed radioisotope sources is being studied as an alternative to enucleation in the treatment of choroidal melanoma and other tumors of the eye. Encouraging early results have been reported, but late complications which lead to loss of vision continue to be a problem. A randomized national study, the Collaborative Ocular Melanoma Stud...

When using a HDR remote afterloading brachytherapy unit, results of treatment can be greatly influenced by both source position and treatment time. The purpose of this study is to obtain information on the source of the HDR remote afterloading unit, such as its position and time structure, with the use of a simple system consisting of a plastic scintillator block and a charge-coupled device (CC...