A 72-year-old patient was referred to our department to carry out an 18F-Choline PET–CT due to biochemical PSA failure from prostate cancer. The patient’s prostate cancer history started 5 years ago when he was diagnosed of a Gleason 3 + 4 tumor and treated with external radiotherapy. Three years later he presented biochemical failure and prostate tumor recurrence. Transrectal biopsy confirmed ...

Monte Carlo simulations are widely used for calculation of the dosimetric parameters of brachytherapy sources. MCNP4C2, MCNP5, MCNPX, EGS4, EGSnrc, PTRAN, and GEANT4 are among the most commonly used codes in this field. Each of these codes utilizes a cross-sectional library for the purpose of simulating different elements and materials with complex chemical compositions. The accuracies of the f...

AIM The aim of this study is to quantify the influence of the photon energy spectrum of brachytherapy sources on task group No. 43 (TG-43) dosimetric parameters. BACKGROUND Different photon spectra are used for a specific radionuclide in Monte Carlo simulations of brachytherapy sources. MATERIALS AND METHODS MCNPX code was used to simulate 125I, 103Pd, 169Yb, and 192Ir brachytherapy sources...

This paper discusses 98 patients who had their cerebral lesions stereotactically biopsied. Modified Riechert-Mundinger instrumentation was employed. Of the 98 patients, eight received only biopsy and 90 were then interstitially radiated with iridium-192 (192Ir) custom stacked in afterloading catheters. The vast majority of brachytherapeutically treated lesions were anaplastic or malignant astro...

A 33-year-old premenopausal multiparous woman with the history of septate uterus was referred to the hospital with menorrhagia and inter-menstrual bleeding occurring for the last 6 months. Work-up revealed a stage IIB cervical cancer. The patient underwent curative chemo/radiotherapy. The patient's septate uterus presented several difficulties during application. Brachytherapy was applied using...

Introduction: 192Ir is one of the important sources frequently used in brachytherapy. Up to now, a lot of commercial models of this source have been made which Ir-192 has been recently added to them. The aim of the present study is to determine the dosimetric parameters of this new source model based on the recommendations of TG-43(U1) protocol using Monte Carlo simulation tech...

Introduction: Passage of ionizing radiation through the organs of living creatures develops clusters of damaged nucleotides inside the DNA rounds. 192Ir Gamma source is one of the most widely used sources in brachytherapy of cervical and prostate cancer. Thus, in this research, we investigated the flux of photons and its resulting secondary electrons, the single-strand break (S...