705 706 708 Reversal of p-Aminobenzoic Acid Inhibition of Growth of Rickettsiae by p-Hydroxybenzoic Acid in Agar-Slant Tissue Culture: N. Takemori and M. Kitaoka . 710 On the Presence of the Triphosphothiamine (TPT) in the Liver: A. Rossi-Fanelli, N. Siliprandi, and P. Fasella . _.711 Comments and Communications Ernest G. Beinhart, H. A. Cole, and Ben Stern .............. 713 Operations Diagnos...

We present three new hybrid copper(II) chloride layered perovskites of generic composition ACuCl4 or A2CuCl4, which exhibit distinct structure types. (m-PdH2)CuCl4 (m-PdH22+ = protonated m-phenylenediamine) adopts a Dion-Jacobson (DJ)-like perovskite type and exhibits very large axial thermal contraction effect upon heating, as revealed via variable-temperature synchrotron X-ray powder diffract...

Pantothenic acid, a portion of the coenzyme A molecule (l), must be supplied in the diet for normal acetylation of p-aminobenzoic acid (PAB) (2) and of sulfanilamide (3) by the rat. Only at certain test levels of PAB, however, is pantothenate deficiency reflected by decreased acetylation (4). The present communication extends the study of the relation between acetylation and size of dose over a...

2-Deamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583) is a potent inhibitor of thymidylate synthase. Its analogue, N(alpha)-[4-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-propargylamino]phenylacetyl]-L-glutamic acid, containing p-aminophenylacetic acid residue substituting p-aminobenzoic acid residue, was synthesized. The new analogue exhibited a moderately potent thy...

The test for exocrine pancreatic function using N-benzoyl-L-tyrosyl-p-aminobenzoic acid (BTPABA test) was assessed in 7 patients with giardiasis and 7 healthy controls. Cumulative percent p-aminobenzoic acid (PABA) recovery in 6 hr was significantly lower in patients with giardiasis, compared with the control group. When an equivalent dose of free PABA was given, there were no differences in PA...

The test for pancreatic exocrine function using N-benzoyl-L-tyrosyl-p-aminobenzoic acid (BTP test) does not require duodenal intubation, but misleadingly abnormal results often occur in patients with liver or bowel disease because the p-aminobenzoic acid (PABA) released by chymotrypsin hydrolysis of the peptide either is not conjugated or is malabsorbed. This study evaluated a modified BTP test...

Many chemically synthesized xenobiotics can significantly inhibit the vitality of parasitic nematodes. However, there is yet too little research on toxicity such contaminating compounds toward Compounds that are present in plants able to organisms as well. According results our laboratory studies toxicity, following caused no decrease larvae Strongyloides papillosus and Haemonchus contortus: me...