Saccharomyces cerevisiae has two haploid cell types, a and alpha, each of which produces a unique set of proteins that participate in the mating process. We sought to determine the minimum set of proteins that must be expressed to allow mating and to confer specificity. We show that the capacity to synthesize alpha-factor pheromone and a-factor receptor is sufficient to allow mating by mat alph...

This paper uses the all-payer claims database (APCD) for Rhode Island to study three questions about use of medication-assisted treatment (MAT) opioid disorder (OUD): (1) Does MAT reduce risk overdose; (2) are there systematic differences in uptake by observable patient-level characteristics; and (3) how successful were federal policy changes implemented 2016 that sought promote increased bupre...

In the heterothallic filamentous fungus Podospora anserina, four mating-type genes encoding transcriptional factors have been characterized: FPR1 in the mat+ sequence and FMR1, SMR1, and SMR2 in the alternative mat- sequence. Fertilization is controlled by FPR1 and FMR1. After fertilization, male and female nuclei, which have divided in the same cell, form mat+/mat- pairs during migration into ...

OBJECTIVE To determine the effectiveness of using a disinfectant mat filled with a peroxygen compound to prevent mechanical transmission of bacteria via contaminated footwear between the food animal ward and common breezeway of a veterinary teaching hospital. DESIGN Observational study. SAMPLE POPULATION Shoe soles of individuals entering and exiting from the ward. PROCEDURES A mat filled...

  Leptospirosis is an acute infectious, systemic and septisemic disease which had recent outbreaks in some parts of Iran especially in north provinces. Rapid detection is a critical step for treatment and control of this disease. In this research a PCR based method was evaluated for detection of Iranian local endemic serovars. All reported endemic serovars of Leptospira including Leptospira gri...

Abstra t. Numeri string is a sequen e of symbols from an alphabet U, where U is some numeri al universe losed under addition and subtra tion. Given two numeri strings A = a 1 a m and B = b 1 b n and a distan e fun tion d(A;B) that gives the s ore of the best (partial) mat hing of A and B, the transposition invariant distan e is min t2U fd(A + t; B)g, where A + t = (a 1 + t)(a 2 + t) : : : (a m ...

Providing access to and utilization of medication assisted treatment (MAT) for the treatment of opioid abuse and dependence provides an important opportunity to improve public health. Access to health services comprising MAT in the community is fundamental to achieve broad service coverage. The type and placement of the health services comprising MAT and integration with primary medical care in...

OBJECTIVES Brucellosis is one of the most common zoonoses in the world, and occurs mainly in farmers, slaughterhouse workers, and veterinarians via direct or indirect contact with infected animals or their products. The clinical symptoms of human brucellosis are nonspecific, such as fever, headache, chills, and sweating. Diagnosis and treatment of brucellosis requires laboratory tests. Although...

Abstra t. Numeri string is a sequen e of symbols from an alphabet U, where U is some numeri al universe losed under addition and subtra tion. Given two numeri strings A = a 1 a m and B = b 1 b n and a distan e fun tion d(A;B) that gives the s ore of the best (partial) mat hing of A and B, the transposition invariant distan e is min t2U fd(A + t; B)g, where A + t = (a 1 + t)(a 2 + t) : : : (a m ...