نتایج جستجو برای: 2 oxo 2h chromenes
تعداد نتایج: 2533418 فیلتر نتایج به سال:
The ammonium salts of many drugs have significantly improved the solubility and, accordingly, bioavailability medicinal substances in human body. 5-(4-Hydroxy-2-oxo-2H-chromen-3-yl)-5H-chromeno[2,3-b]pyridines are potential NPY1R ligands, which attractive for antiobesity treatment. Ammonium 5H-chromeno[2,3-b]pyridines were previously unknown. In this communication, it was found that four-compon...
6-carbethoxy-5-(3'-bromophenyl)-3-aryl-2-cyclohexenones 2a-j were obtained from the1-aryl-3-(3'-bromophenyl)-2-propene-1-ones 1a-j by micheal addition of ethyl acetoacetate, followed by internal claisen condensation. reaction of 2a-j with hydrazine hydrate afforded the corresponding 6-aryl-4-(3'-bromophenyl)-3-oxo-2,3a,4,5-tetrahydro-2h-indazoles 3a-j. the structures of newly syn...
An convenient one-pot approach for the synthesis of new (E)-2-(2-oxo-4-phenylbut-3-en-1-yl)benzo[d]thiazole-3(2H)-carboxylates is demonstrated. The method based on a three-component reaction benzylideneacetone with electrophilic N-alkoxycarbonylbenzothiazolium species formed in situ. newly synthesized compounds were fully characterized by 1D 1H, 13C- NMR, IR and MS.
New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamide derivatives and a wide range of coumarins. The structures of compounds were elucidated by IR and NMR spectra and also analytical elemental analysis. In the next step, the above mentioned compounds ...
6-Carbethoxy-5-(3'-bromophenyl)-3-aryl-2-cyclohexenones 2a-j were obtained from the1-Aryl-3-(3'-bromophenyl)-2-propene-1-ones 1a-j by Micheal addition of ethyl acetoacetate, followed by internal Claisen condensation. Reaction of 2a-j with hydrazine hydrate afforded the corresponding 6-Aryl-4-(3'-bromophenyl)-3-oxo-2,3a,4,5-tetrahydro-2H-indazoles 3a-j. The structures of newly synthesized compou...
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