Most cancer treatments exploit the hypersensitivity of rapidly dividing tumor cells to DNA damage, largely reflecting problems with replicating damaged DNA templates. Many cancer chemotherapeutics directly damage DNA, and most types of DNA damage block replication forks. Other classes of chemotherapeutics include antimetabolites that reduce nucleotide pools and starve DNA polymerases or directl...

Analogy researchers do not often examine gesture, and gesture researchers do not often borrow ideas from the study of analogy. One borrowable idea from the world of analogy is the importance of distinguishing between attributes and relations. Gentner (, ) observed that some metaphors highlight attributes and others highlight relations, and called the latter analogies. Mirroring this logic, we o...

How to provide users a positive experience during interaction with information (i.e., the “Information eXperience” (IX)) is still an open question. As a starting point, this work investigates how the emotion of interest can be influenced by modifying the complexity of the information presented to users. The appraisal theory of interest suggests a “sweet spot” where interest will be at its peak:...

Haptic interaction has for a long time been a promise that has not fully been realized in everyday technology due to several reasons. Already for more than 20 years the research community in the field of human-technology interaction has identified multimodal interaction as a potential next mainstream interaction paradigm to replace graphical user interfaces. At the same time, both personal comp...