Diabetes is a serious public health problem and is widely recognized as one of the major health emergencies of the latest years [1,2]. Global diabetes prevalance is projected to rise from 415 million in 2015 to 642 million in 2040. In other words, the risk of diabetes will rise markedly, from one in 11 adults in 2015, to one in 10 adults by 2040. It is estimated by the International Diabetes Fe...

www.thelancet.com Vol 386 August 15, 2015 643 Looking into the future often creates a mixture of uncertainty and anticipation. Science fi ction is fi lled with stories of doom and excitement about discoveries yet to be made. The UK Academy of Medical Sciences is exploring what the main health challenges for the UK population will be in 2040, and identifying opportunities to address them. To coi...

Understanding the likely impacts of climate change (CC) and Land Use Cover (LULC) on water resources (WR) is critical for a basin’s mitigation. The present study intends to quantify impact streamflow (SF) Parvara Mula Basin (PMB) using SWAT. SWAT model was calibrated validated Calibration Uncertainty Program (SWAT-CUP) two time periods (2003–2007 2013–2016) (2008–2010 2017–2018), respectively. ...

Background TRAIL is present in cells involved in asthma including eosinophils, mast cells, fibroblasts, and airway epithelial cells. It is expressed in airway remodeling and may be linked with the pathways of transforming growth factorbeta1, which is thought to cause damage to the epithelium. The repair process of the epithelium is hindered as a result of increased apoptosis induced by TGF-beta...