This study was performed to test the hypothesis that long-term nitric oxide synthase (NOS) inhibition during pregnancy may alter the predominance of the vasodilator kallikrein system. Sprague-Dawley rats were treated with the competitive inhibitor of NOS N(omega)-nitro-L-arginine (L-NNA, 50 mg. kg(-1). d(-1), dissolved in water) from days 7 to 21 of pregnancy. Rats were studied before treatment...

This study assessed the efficacy of anorganic bone mineral coated with P-15 peptide (ABM/P-15) on tibia defect repair longitudinally in both normal and osteoporotic rats in vivo. A paired design was used. 24 Norwegian brown rats were divided into normal and osteoporotic groups. 48 cylindrical defects were created in proximal tibias bilaterally. Defects were filled with ABM/P-15 or left empty. O...

Canine mesenchymal cells (MSCs) derived from Wharton's jelly were co-cultured, then supplemented or not supplemented with platelet rich plasma (PRP) and demineralized bone matrix (DBM) to verify osteogenic differentiation. Osteoblastic differentiation followed by mineralized bone matrix production was found to be significantly higher (p < 0.05) when MSCs were associated with PRP/DBM in culture ...

OBJECTIVE This study evaluated the relationship between nutritional intake and protein and caloric requirements and observed clinical outcomes on the 7th day of intensive care unit stay. METHODS This was a retrospective cohort study of 126 patients who were admitted to the intensive care unit for >7 days. The patients were categorized according to the adequacy of energy and protein intake in ...

Phenology of vegetation is a sensitive and valuable indicator of the dynamic responses of terrestrial ecosystems to climate change. Therefore, to better understand and predict ecosystems dynamics, it is important to reduce uncertainties in detecting phenological changes. Here, changes in phenology over the past several decades across the northern high-latitude region (≥60N) were examined by cal...

The study was designed to compare the growth performance, digestibility and concentration of phosphorous (P) and calcium (Ca) in blood plasma, tibia bone and excreta in juvenile birds fed different commercially available sources of inorganic P. Day-old Hubbard broiler chickens (180) were randomly assigned to one of 4 dietary treatments (A-D), replicated three times with 15 birds per cage. All d...

BACKGROUND The potential health benefits of ω-3 polyunsaturated fatty acids (PUFAs) usually are studied using a combination of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). This combination reduces vulnerability to experimentally induced atrial fibrillation (AF). It is unknown whether EPA and DHA have differential effects when taken alone. Using a model of pacing-induced atrial he...

BACKGROUND Nomegestrol acetate/17β-estradiol (NOMAC/E(2)) is a new monophasic oral contraceptive combining NOMAC (2.5 mg), a highly selective progesterone-derived progestogen, with E(2) (1.5 mg), which is structurally identical to endogenous estrogen. The objective of this study was to compare the effects on ovarian activity of two different NOMAC/E(2) regimens. METHODS This was a double-blind,...

The objective of this study was to evaluate the antidiabetic activities of methanol and aqueous extracts of Pergularia daemia in alloxan induced diabetic rats. Methods used was methanol and aqueous extracts (250 mg/kg b.w.) of P. daemia was administered to alloxan induced diabetic mice for 21 days and blood glucose levels of the diabetic rats were monitored at intervals of hours and days throug...

The purpose of this experiment was to determine the effects of high environmental temperature on the blood indices (mean corpuscular volume, MCV; mean corpuscular hemoglobin, MCH; mean corpuscular hemoglobin concentration, MCHC) of Thai Indigenous Chickens (TIC), Thai Indigenous Chickens Crossbred (TICC) and broilers (BC). One kilogram of male and female TIC, TICC and BC were maintained in an e...