BACKGROUND Human brucellosis is usually treated with a combination of tetracyclines and aminoglycosides. However, the optimal duration of therapy has not been clearly determined. METHODS We conducted a prospective, double-blind, randomized, multicenter study comparing treatment with doxycycline (100 mg po b.i.d.) for 30 days (30-day group) with the same dosage of doxycycline for 45 days (45-d...

OBJECTIVES Twenty years ago our institution published an analysis of a cluster of failures associated with the arterial switch operation (ASO). The concept of 'near miss' was explored to detect warning signs of suboptimal performance. The aim of the current study was to review the parameters best suited to monitoring early ASO outcomes in the modern setting and re-examine the concept of near mi...

Prolonged sinus or atrial pause occurred in six patients with paroxysmal supraventricular tachycardia after drug administration. All six patients had normal sinus node function during control electrophysiologic study; the sinus cycle length ranged from 510 to 900 ms (mean 743 +/- 141) and the longest sinus node recovery time ranged from 800 to 1,230 ms (mean 1,018 +/- 168). A long sinus or atri...

The course has been suggestive ofa hypersensitivity reaction with a shorter period to development ofabnormal liver function after re-exposure to the drug. Ours is the first case with typical pathological features of chronic active hepatitis. The evidence strongly implicated cimetidine. Inadvertent re-exposure to the drug caused rapid recurrence of jaundice and abnormal liver function values, an...

There are many applications which arise in telecommunications information processing in which it is useful, and often necessary, to create and access multiple hypothetical states. These might correspond to future states reeecting pending updates (such as customer service orders), or hypothetical alternative states that would arise in the exploration of diierent solutions to a given problem. In ...

Background: Critically ill patients are at risk of malnutrition; thus, optimal nutrition delivery is a key treatment for better outcomes. Inadequate energy and protein intake increase rate hospital-acquired infection, duration mechanical ventilation mortality. However, there no clear consensus regarding dose in mechanically ventilated patients. In this study, we aim to compare between the effec...

Abstract The genus Pouteria has been studied because it presents various activities, among which is its anti-inflammatory potential. effects of ramiflora Carbopol gel on the healing skin wounds in diabetic rats were evaluated by microscopic imaging. Streptozotocin was administered intraperitoneally animals that had fasted for 12 hours, a situation confirmed glycemic index (˃ 240 mg dL-1). An ex...