نتایج جستجو برای: 275 and 66

تعداد نتایج: 16839353  

A. Javanmard A. Ostadi A. Seifi M. Amani Machiani S. Khodayari

Intercropping is a sustainable practice to achieve higher production with the aim to limit external inputs. A field experiment was conducted at the research farm of the Faculty of Agriculture, University of Maragheh, Maragheh, Iran, during 2016 growing seasons with ten treatments to evaluate the yield, analyze the competition and insect’s assemblages in sunflower (as main plant)/soybean (as com...

Journal: :Journal of Glaciology 2023

An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.

Journal: :Journal of Glaciology 2023

An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.

Journal: :Cancer research 2001
B I Lee S H Park J W Kim E A Sausville H T Kim O Nakanishi J B Trepel S J Kim

Transcriptional repression of the transforming growth factor (TGF)-1P type II receptor (TPRII) gene appears to be a major mechanism to inactivate TGF-beta responsiveness in many human cancers. Because histone acetylation/deacetylation plays a role in transcriptional regulation, we have examined the effect of MS-275, a synthetic inhibitor of histone deacetylase, in human breast cancer cell lines...

Journal: :Molecular cancer therapeutics 2006
Ilker Y Eyüpoglu Eric Hahnen Christian Tränkle Nicolai E Savaskan Florian A Siebzehnrübl Rolf Buslei Dieter Lemke Wolfgang Wick Rudolf Fahlbusch Ingmar Blümcke

Inhibitors of histone deacetylases are promising compounds for the treatment of cancer but have not been systematically explored in malignant brain tumors. Here, we characterize the benzamide MS-275, a class I histone deacetylase inhibitor, as potent drug for experimental therapy of glioblastomas. Treatment of four glioma cell lines (U87MG, C6, F98, and SMA-560) with MS-275 significantly reduce...

Journal: :Australasian J. of Inf. Systems 1998
Andrew Burton John Mooney

Evolving competitive, organisational and technology environments drive organisations to continually evaluate how information technology resources can be exploited for competitive value. The emergence of a global information infrastructure has spawned an entirely new area for competitive exploitation, electronic marketplaces. This paper first presents a review and synthesis of the conceptual and...

2002
Billie L. Turner

exceeded anything that the Earth has experienced for millions of years, and the growth rate has been unprecedented. But such long-term views are sometimes hard to grasp. What is the timescale relevant for society today? Perhaps it is more instructive to consider just the period over which civilization has developed, from the time when the first cities were established around 6000 years ago. If ...

Journal: :CoRR 2014
Owen Sims Robert P. Gilles

Critical nodes—or “middlemen”—have an essential place in both social and economic networks when considering the flow of information and trade. This paper extends the concept of critical nodes to directed networks. We identify strong and weak middlemen. Node contestability is introduced as a form of competition in networks; a duality between uncontested intermediaries and middlemen is establishe...

2017

ARHA110 Introduction to Western Art: Renaissance to Modern This course surveys the development of Western art from the Renaissance through the modern period. We will examine art's changing status within specific social and artistic contexts: from the Church and court of the Renaissance, through the formation of art academies in late 16th century, to the development of an increasingly individual...

Journal: :Anticancer research 2006
Noriyuki Takai Tami Ueda Masakazu Nishida Kaei Nasu Hisashi Narahara

BACKGROUND Histone deacetylase inhibitors (HDACIs) can inhibit cell proliferation, induce cell cycle arrest and stimulate apoptosis of cancer cells. MATERIALS AND METHODS The effects of a novel HDACI, MS-275, on 4 endometrial cancer cell lines and normal human endometrial epithelial cells was investigated. Endometrial cancer cells were treated with various concentrations of MS-275 and its eff...

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