Blakley, R. L. (1985) in Folates and Pterins (Blakley, R. L. & Benkovic, S. J., eds.), vol. 1 , pp. 191 -253, Wiley, New York Bolin, J. T., Filman, D. J., Matthews, D. A., Hamlin, R. C. & Kraut, J. ( 1982) J. Biol. Chem. 257, 1365013662 Clore, G. M., Gronenborn, A. M., Birdsall, B., Feeney, J. & Roberts, G. C. K. ( 1984) Biochem. J. 2 17,659-666 Feeney, J. (1986) in NMR in Living Systems (Axenr...

The possibility of the existence of quark stars has been discussed by several authors since 1970. Recently, it has been pointed out that two putative neutron stars, RXJ 1856.5-3754 in Corona Australis and 3C58 in Cassiopeia are too small and too dense to be neutron stars; they show evidence of being quark stars. Apart from these two objects, there are several other compact objects which fit nei...

We examined the effect of several nitric oxide (NO) donors, authentic NO gas, and L-arginine in isolated cat and rat papillary muscles. We did not observe significant inotropic effects in response to any NO donor (ie, SPM-5185, C87-3754, and S-nitroso-N-acetylpenicillamine [SNAP]) from 1 nmol/L to 100 mumol/L. Similarly, authentic NO, at concentrations far in excess of those that maximally dila...

Mast cells represent a crucial cell type in host defense; however, maladaptive responses are contributing factors in the pathogenesis of allergic diseases. Previous work in our laboratory has shown that exposure to silver nanoparticles (AgNPs) results in mast cell degranulation via a non-immunoglobulin E (IgE) mechanism. In this study, we utilized a systems biology approach to identify novel ge...

Midwest U.S. herds (n=63) were studied to identify risk factors for harboring Salmonella enterica among slaughter-weight pigs. Samples collected on farms (feces) and at slaughter (distal colonic content, cecal content and ileocolic lymph nodes) were cultured using conventional means. Approximately 15 pigs were studied per herd, for a total of 3754 samples. The proportion of pigs positive in one...

BACKGROUND Although rectal bleeding in infancy (RBI) is not a rare phenomenon, the clinical course of RBI is not fully understood. METHODS To investigate the outcome and pathogenesis of RBI, especially when concomitant with food-protein-induced proctocolitis (FPIP) and neonatal transient eosinophilic colitis (NTEC), 22 neonates with rectal bleeding with FPIP and NTEC from January 2008 to June...

We derive a new set of equations which describe a continuous one parameter family of expanding wave solutions of the Einstein equations such that the Friedmann universe associated with the pure radiation phase of the Standard Model of Cosmology, is embedded as a single point in this family. All of the spacetime metrics associated with this family satisfy the equation of state p = ρc/3, correct ...

BACKGROUND The Swiss government decided to freeze new accreditations for physicians in private practice in Switzerland based on the assumption that demand-induced health care spending may be cut by limiting care offers. This legislation initiated an ongoing controversial public debate in Switzerland. The aim of this study is therefore the determination of socio-demographic and health system-rel...