6 1 State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, CAAS, 7 427 Maduan Street, Harbin 150001, P. R. China 8 2 Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan 9 3 ERATO Infection-Induced Host Responses Project, Saitama 332-0012, Japan 10 4 Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, ...

Mouse organic anion transporter 1 (mOAT1) belongs to a family of organic anion transporters, which play critical roles in the body disposition of clinically important drugs, including anti-HIV therapeutics, anti-tumour drugs, antibiotics, anti-hypertensives and anti-inflammatories. mOAT1-mediated transport of organic anion PAH ( p -aminohippurate) in HeLa cells was inhibited by the cysteine-mod...

The alphaB-crystallin/small heat shock protein gene is expressed very highly in the mouse eye lens and to a lesser extent in many other nonocular tissues, including the heart, skeletal muscle and brain. Previously we showed in transgenic mice that lens-specific alphaB-crystallin promoter activity is directed by a proximal promoter fragment (-164/+44) and that non-lens promoter activity depends ...

The model presented here extends formal analysis (Hasselmo et al., Neural Networks, 15, pp. 689–707, 2002b) and abstract modelling (Gorchetchnikov and Hasselmo, Neuro Computing, 44–46, pp. 423–427, 2002a) of interactions within the hippocampal area (or other cortical areas), which can be flexibly used to navigate toward any arbitrary goal or multiple goals that change on a trial-by-trial basis....

A molecular phylogenetic analysis of 25 isolates of fish nodaviruses, the causative agents of viral nervous necrosis of marine fish, was performed based on the nucleotide sequences (427 bases) of the coat protein gene. These fish nodaviruses were classified into four clusters: tiger puffer nervous necrosis virus, striped jack nervous necrosis virus, berfin flounder nervous necrosis virus, and r...

INTRODUCTION ........................................ 419 GENE ORGANIZATION ........................................ 419 TEMPORAL EXPRESSION OF EARLY GENES ........................................ 420 TRANSCRIPTION CONTROL........................................ 421 ACTIVATION OF TRANSCRIPTION BY ElA 421 Mechanism for E1A Action ........................................ 423 E2F Factor .............