نتایج جستجو برای: 5 methylcytosine

تعداد نتایج: 1216212  

Journal: :Cold Spring Harbor Symposia on Quantitative Biology 2013

Journal: :Trends in genetics : TIG 2009
Mary Gehring Wolf Reik Steven Henikoff

Active DNA demethylation underlies key facets of reproduction in flowering plants and mammals and serves a general genome housekeeping function in plants. A family of 5-methylcytosine DNA glycosylases catalyzes plant demethylation via the well-known DNA base-excision-repair process. Although the existence of active demethylation has been known for a longer time in mammals, the means of achievin...

2014
Oliver Smith Alan J. Clapham Pam Rose Yuan Liu Jun Wang Robin G. Allaby

Genomic methylation is variable under biotic and abiotic stresses in plants. In particular, viral infection is thought to significantly increase genomic methylation with particularly high activity around transposable elements. Here we present the genomic methylation profiles of grains of archaeological barley (Hordeum vulgare) from several strata from a site in southern Egypt, from the Napatan ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Mario F Fraga Esteban Ballestar Maria F Paz Santiago Ropero Fernando Setien Maria L Ballestar Damia Heine-Suñer Juan C Cigudosa Miguel Urioste Javier Benitez Manuel Boix-Chornet Abel Sanchez-Aguilera Charlotte Ling Emma Carlsson Pernille Poulsen Allan Vaag Zarko Stephan Tim D Spector Yue-Zhong Wu Christoph Plass Manel Esteller

Monozygous twins share a common genotype. However, most monozygotic twin pairs are not identical; several types of phenotypic discordance may be observed, such as differences in susceptibilities to disease and a wide range of anthropomorphic features. There are several possible explanations for these observations, but one is the existence of epigenetic differences. To address this issue, we exa...

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