SUMMARY Structured approaches are beneficial for successful software process improvement (SPI). However, process engineers often struggle with standardized SPI methods, such as CMMI or ISO 15504, and complain about too generic or voluminous approaches, or methods that are alien to the organizations in which SPI is conducted. Therefore, process engineers need to customize existing SPI models or ...

Meteorological drought monitoring is important for drought early warning and disaster prevention. Regional meteorological drought can be evaluated and analyzed with standardized precipitation index (SPI). Two main processing schemes are frequently adopted: (1) mean of all SPI calculated from precipitation at individual stations (SPI-mean); and (2) SPI calculated from all-station averaged precip...

Leukemic cells from a child with acute lymphoblastic leukemia (ALL) had high natural killer (NK) activity against K562 as determined by the 51Cr release assay at a 40:1 effector:target ratio: percent lysis was 76.8% (147.4% of normal lymphocyte value) and higher than that of control leukemic cells from 12 childhood ALL (0.1% +/- 0.3%). Two leukemic cell lines (SPI-801 and SPI-802) were establis...

Amino acid composition and isoflavone are alleged contributors to the beneficial effects of soy protein isolate (SPI) on lipid metabolism. Therefore, we investigated the contributing component(s) of SPI in a maternal diet to the regulation of lipid metabolism in offspring. We also determined serum parameters in dams to investigate specific maternal cues that might be responsible for this regula...

SCOPE The long-term effect of exposure to relevant dietary levels of genistein (GEN) on estrogen receptor-positive (ER+) human breast cancer (MCF-7) progression after GEN withdrawal in athymic mice xenograft model was studied. MATERIALS AND METHODS Feeding studies were conducted to determine the estrogenic effect of diets on MCF-7 tumor growth: (1) implantation (19 weeks) and withdrawal (6 we...

A meteorological drought study is performed using monthly time scale data from three separate locations in southern Sindh, Pakistan. Rainfall and temperature have been used to identify the drought. These were transformed into indices known as standardized precipitation evapotranspiration index (SPEI) (SPI), which derived (the Hargreaves equation). In this study, two are compared for stations Ch...

This paper evaluates climate change effects on drought severity in the region of Thessaly, Greece. The Standardized Precipitation Index (SPI) has been used for estimation of drought severity. A geographical information system is applied for the division of Thessaly region to twelve hydrological homogeneous areas based on their geomorphology. Mean monthly precipitation values from 50 precipitati...

Offspring of female rats fed either a casein (CAS) diet or a low-isoflavone soy protein isolate (SPI) diet were compared in an animal model of chronic ethanol consumption to investigate whether maternal diet regulates the adaptive responses of offspring to postnatal ethanol exposure and potentially affects the development of liver disease in later life. Female rats were fed either a CAS or an S...

Ectromelia virus (ECTV) is a natural pathogen of mice that causes mousepox, and many of its genes have been implicated in the modulation of host immune responses. Serine protease inhibitor 2 (SPI-2) is one of these putative ECTV host response modifier proteins. SPI-2 is conserved across orthopoxviruses, but results defining its mechanism of action and in vivo function are lacking or contradicto...

The present study evaluated the anti-inflammatory activity of a polysaccharide from maté, using a clinically relevant model of sepsis induced by cecal ligation and puncture (CLP). A polysaccharide from maté (SPI) was obtained from aqueous extraction followed by fractionation, being identified as a rhamnogalacturonan with a main chain of →4)-6-OMe-α-D-GalpA-(1→ groups, interrupted by α-L-Rhap un...