INTRODUCTION Mohs micrographic surgery (MMS) is the treatment of choice for high-risk facial basal cell carcinoma (BCC) as it offers the greatest chance of cure with maximum preservation of healthy tissue. Its use in Spanish public health care hospitals is still limited, however, due to the controversy surrounding its cost. OBJECTIVES To determine the cost of MMS with fresh tissue to treat hi...

Der Arbeitskreis Blickbewegung wurde während der 6. Berliner Werkstatt MenschMaschine-Systeme durchgeführt. Die 6. Werkstatt MMS widmete sich der Zustandserkennung und Systemgestaltung. Neben Modellierungsansätzen und Forschungsberichten standen v.a. auch die Methoden zur Erkennung verschiedener Phänomene, wie z.B. Müdigkeit und Beanspruchung im Vordergrund. Im Arbeitskreis Blickbewegung wurden...

BACKGROUND Mohs micrographic surgery (MMS) has a low rate of surgical site infection (SSI) without the use of prophylactic antibiotics. In the studies to date, there has been variation in the steps taken by each surgeon to prevent SSIs but in all cases sterile technique was used during wound reconstruction. OBJECTIVE We sought to evaluate the rate of SSIs among patients undergoing MMS with th...

BACKGROUND Mohs micrographic surgery (MMS) is used to treat certain high-risk non-melanoma skin cancers (NMSC) due to its high cure rate. However, clinical recurrences do occur in a small number of cases. OBJECTIVE We examined specific clinical characteristics associated with NMSC recurrences following MMS. METHODS We employed a retrospective chart review of the 1467 cases of NMSC that unde...

Objectives. To study the utility of the Mini-Cog test for detection of patients with cognitive impairment (CI) in primary care (PC). Methods. We pooled data from two phase III studies conducted in Spain. Patients with complaints or suspicion of CI were consecutively recruited by PC physicians. The cognitive diagnosis was performed by an expert neurologist, after formal neuropsychological evalua...

We hereby present different DNA nanocarriers consisting of new multimodular systems (MMS), containing the cationic lipid dioleylaminesuccinylparomomycin (DNA MMS DOSP), or bis (guanidinium)-tren-cholesterol (DNA MMS BGTC), and DNA lipid nanocapsules (DNA LNCs). Active targeting of the asialoglycoprotein receptor (ASGP-R) using galactose as a ligand for DNA MMS (GAL DNA MMS) and passive targetin...

We present a lattice determination of the charm quark’s mass, using the mass of the Ds meson as experimental input. All errors are under control with the exception of the quenched approximation. Setting the scale with FK = 160MeV, our final result for the renormalization group invariant (RGI) quark mass is Mc = 1.654(45)GeV, which translates to mMS c (mc) = 1.301(34)GeV for the running mass in ...

BACKGROUND The clinical application of nimodipine (NIM) is limited by several unfavorable properties, which are induced by its low aqueous solubility. In the present study, nimodipine-loaded egg phosphatidylcholine-sodium glycocholate mixed micelles (NIM-EPC-SGC-MMs) were prepared to improve the water solubility of NIM, thus allowing it to be more applicable for clinical use. METHODS NIM-EPC-...

In the information systems (IS) literature, there is a gap in understanding the role of middle managers (MMs) in the digital transformation in organizations. IS research has focused on understanding top management and user roles in IT-related transformational change but the role of MMs has rarely been examined. To fill this gap, this paper reports on an open-ended exploration of the influence a...

To better understand alkylating agent-induced cytotoxicity and the base lesion DNA repair process in Saccharomyces cerevisiae, we replaced the RAD27(FEN1) open reading frame (ORF) with the ORF of the bifunctional human repair enzyme DNA polymerase (Pol) β. The aim was to probe the effect of removal of the incised abasic site 5'-sugar phosphate group (i.e., 5'-deoxyribose phosphate or 5'-dRP) in...