BACKGROUND Recent evidence suggests that a low carbohydrate (LC) diet may be equally or more effective for short-term weight loss than a traditional low fat (LF) diet; however, less is known about how they compare for weight maintenance. The purpose of this study was to compare body weight (BW) for participants in a clinical weight management program, consuming a LC or LF weight maintenance die...

CONTEXT Rapid increases in access to the Internet have made it a viable mode for public health intervention. No controlled studies have evaluated this resource for weight loss. OBJECTIVE To determine whether a structured Internet behavioral weight loss program produces greater initial weight loss and changes in waist circumference than a weight loss education Web site. DESIGN Randomized, co...

BACKGROUND The purpose of this study was to evaluate the effects of milnacipran on body weight in patients with fibromyalgia. METHODS ANALYSES WERE CONDUCTED IN THE FOLLOWING GROUPS: patients from three double-blind, placebo-controlled milnacipran trials (3 months, n = 2096; 6 months, n = 1008); 354 patients receiving milnacipran in placebo-controlled trials and double-blind extension studies...

BACKGROUND Fibroblast growth factor 21 (FGF21) is a metabolic and growth regulator. AIM To investigate the role of FGF21 during growth in infancy. METHODS Blood samples for FGF21, leptin, insulin and glucose were collected from cord blood obtained from 95 preterm and term newborns (cross-sectional group), and at 6 and 12 months of life in 80 preterm and term infants (longitudinal group). Le...

BACKGROUND Exenatide, a GLP-1 analogue, is used in combination with oral anti-diabetic agents in type 2 diabetes and obesity, and promotes weight loss. Exenatide use in combination with insulin in insulin-treated type 2 diabetes and obesity is unlicensed in the UK and outcomes are unclear. AIMS To assess the effectiveness of exenatide in insulin-treated type 2 diabetes with obesity. DESIGN ...

OBJECTIVE To compare results of a conventional obesity treatment program with those of an obesity treatment program that included education of owners of obese dogs. DESIGN Nonblinded prospective clinical trial. ANIMALS 60 obese dogs with a body condition score (BCS) of 8/9 or 9/9. PROCEDURE Dogs were randomly assigned to control or owner education (EDU) treatment groups. A 6-month weight ...