A latex agglutination test for the detection of Pseudomonas pseudomallei antigen in urine was evaluated for the rapid diagnosis of melioidosis. With unconcentrated urine, antigen was detected in only 18% of patients with melioidosis overall. However, when urine was concentrated 100-fold, antigen was detected in 47% overall and in 67% of patients with septicaemia or disseminated infection, in wh...

PURPOSE AND EXPERIMENTAL DESIGN The purpose is to define intratumoral microvessel density (MVD) and potential biological markers that correlate with inflammatory breast cancer (IBC), we examined MVD, estrogen receptor a (ER) status, MIB-1 proliferation index, p53, and c-erbB-2 by immunohistochemistry in archival specimens from 67 women diagnosed with breast cancer with or without the inflammato...

BACKGROUND Hemangiopericytoma (HPC) of the head and neck is a rare neoplasm whose biologic behavior is difficult to predict by means of conventional histologic parameters. METHODS H & E-stained sections from 12 cases of HPC were reviewed. Proliferation index was assessed using an immunoperoxidase stain for MIB-1 (Ki-67). RESULTS The study group consisted of 4 adult men, 5 adult women, and 1...

Reduced neurogenesis in the aging mammalian hippocampus has been linked to cognitive deficits and increased risk of dementia. We utilized postmortem human hippocampal tissue from 26 subjects aged 18-88 years to investigate changes in expression of six genes representing different stages of neurogenesis across the healthy adult lifespan. Progressive and significant decreases in mRNA levels of th...

1854 People often have difficulty retrospectively determining the level of knowledge they had prior to acquiring new knowledge (e.g., Fischhoff, 1975; Hasher, Attig, & Alba, 1981; Wood, 1978). Fischhoff (1977) coined the phrase knew-it-all-along (KIA) effect to describe this phenomenon, although it also is commonly referred to as hindsight bias. In a typical KIA paradigm, participants respond t...

Adenoid cystic carcinoma (AdCC) and polymorphous low-grade adenocarcinoma (PLGA) have several common histological and clinicopathological features that may create diagnostic difficulties. In this study, 10 AdCCs, 8 PLGAs, and 5 normal minor salivary glands as a control group were selected. Sections prepared from each tumor were stained using the streptavidin-biotin system for seven marker antig...

BACKGROUND The purpose of the present study was to analyze the recurrence pattern of high-grade glioma treated with a multimodal treatment approach and to evaluate whether the MIB-1 labeling index (LI) could be a useful marker for predicting the pattern of failure in glioblastoma (GB). METHODS AND MATERIALS We evaluated histologically confirmed 131 patients with either anaplastic astrocytoma ...

Kia Homayounfar ([email protected]) Johanna Meis ([email protected]) Klaus Jung ([email protected]) Bernd Klosterhalfen ([email protected]) Thilo Sprenger ([email protected]) Lena-Christin Conradi ([email protected]) Claus Langer ([email protected]) Heinz Becker (hbecker@chirurgie-go...

One of the most important questions in clinical routine is to find out patients with good or worse prognosis to apply an optimal therapy scheme for each patient. In this study 58 patients with different neuroendocrine tumours of the lung were investigated. Histological sections were prepared with different stainings (MIB-1, AgNOR, Feulgen). By means of high resolution image cytometry stereologi...

The chemical name of the title compound in the paper by Kia, Fun & Kargar [Acta Cryst. (2009), E64, o2406] is corrected.[This corrects the article DOI: 10.1107/S1600536809023320.].