background and objective: parkinson's disease (pd) is an age-related neurodegenerative disease with selective damage of dopaminergic neurons of the mesencephalon. l-dihydroxyphenylamine (l-dopa) therapy is currently the gold standard maneuver for pd. due to the protective, anti-inflammatory, and antioxidant effect of sesamin, this study was undertaken to assess dose-dependent effect of this age...

Electrical stimulation of the superior colliculi of alert, behaving monkeys evoked all-or-nothing saccades whose amplitude and direction were independent of stimulus parametersand depth within the colliculus. They were also independent of initial eye position and werethus not goal-directed. Across the colliculus, the saccades were small (1”) rostrally, large (50”)caudally with u...