Povzetek. Sodobne organizacije se spreminjajo zelo pogosto. Spremembe se poskuša izvesti hitro in učinkovito. Spremembe pogosto vključujejo spremembe IS zaradi njegovega pomena v organizacijah. Odpor do sprememb spada med ključne dejavnike uspeha večjih projektov in programov IT. Obvladovanje odpora ne pomaga organizacijam zgolj izvesti spremembe hitreje in učinkoviteje, temveč je hkrati tudi p...

PURPOSE Long-acting β2-agonists (LABAs) have demonstrated efficacy in patients with COPD in clinical trials. The purpose of this study was to assess the comparative efficacy of all available dosages of all LABA monotherapies using a network meta-analysis. METHODS A systematic literature review identified 33 randomized controlled trials of LABA monotherapies (salmeterol 50 μg twice daily [BID]...

BACKGROUND Oral liarozole, a retinoic acid metabolism-blocking agent, may be an alternative to systemic retinoid therapy in patients with lamellar ichthyosis. OBJECTIVE To demonstrate the efficacy and safety of once-daily oral liarozole in the treatment of moderate/severe lamellar ichthyosis. METHODS This was a double-blind, multinational, parallel phase II/III trial (NCT00282724). Patients...

Vision is suppressed during blinks and saccadic eye movements. We hypothesized that visual reaction times (RTs) in a vigilance test would be significantly increased when a blink or a saccade happened to coincide with the stimulus onset. Thirty healthy volunteers each performed a visual RT test for 15 min while their eye and eyelid movements were monitored by a system of infrared reflectance ocu...

A dose/response study has been carried out in seven patients with endoscopically proven duodenal ulcers in symptomatic remission, measuring intragastric pH and gastric acid output overnight after a bedtime dose of ranitidine (75 mg, 150 mg, and 300 mg); and the results have been compared with placebo and with bedtime cimetidine 400 mg. The currently recommended ranitidine maintenance dose (150 ...

Dieldrin accumulation and elimination in muscle tissue of channel catfish (Ictalurus punctatus) from water and food was determined in the laboratory. Twenty-eight-day exposure of fish 150-225 mm and 350-400 mm long to 75 parts per trillion (ng/liter) dieldrin resulted in the larger catfish consistently accumulating more dieldrin than the smaller fish. After 28 days of elimination, dieldrin leve...

The effect of pirenzepine on 24 hour intragastric acidity was studied in 10 healthy volunteers using ambulatory 24 hour intragastric pH-monitoring in a double blind crossover study. Tests were performed on the seventh day of ingestion of either placebo, 75 mg pirenzepine or 150 mg pirenzepine per day. The drugs were given at two doses at 8.30 am and 8.30 pm. Mean nocturnal hydrogen ion activity...

Nitrogen influence plant growth and yield of crops. To evaluate the potential different pre released rice genotypes at levels under Northern Telangana Zone. Experiment was laid out insplit plot design with five main plots (pre cultures) four sub (nitrogen levels) RARS, Jagtial, Kharif 2018-19 to Rabi 2019-20.
 Four cultures TelaganaZone viz., C1-KNM-733, C2- KNM-1638, C3- JGL 24423 C4: JGL...