We assume two loci under selection (A and B) and a third neutral locus C, each with two alleles denoted by A1 and A2, B1 and B2, and C1 and C2, respectively. Let the frequencies of alleles A1, A2, B1, B2, C1 and C3 be p, 1 p, q, 1 q, n and 1 n, respectively. We denote the recombination rate between locus i and j by rij and consider a continuous-time model, such that second-order terms of recomb...

parent ACsEx.A Concrete children ACsEx.B1, ACsEx.B2, ACsEx1.B3 Class ACsEx.B1: Inherited methods B1.a2(), B1.a3(), B1.a4(P), B1.a7() Class ACsEx.B2: Inherited methods B2.a1(P), B2.a4(P), B2.a6(), B2.a7(), B2.a8(int) Class ACsEx1.B3: Inherited methods B3.a4(P), B3.a6(), B3.a7(), B3.a8(int) for the classes ACsEx.A, ACsEx.B1, ACsEx.B2, and ACsEx1.B3 from the code in Figure 1, the data in Table IV ...

We present a range of estimates for future radiative forcings due to changes in tropospheric ozone (O3T ). Ozone distributions were generated by the UKMO 3-D chemistry-transport model for 1990, 2030, 2060, and 2100, using four sets of boundary conditions. Anthropogenic emissions evolved following either the IPCC SRES “high” (A2) or “central” (B2) case. Each scenario was run with both a fixed (1...

INTRODUCTION Non-alcoholic fatty liver disease (NAFLD), a hepatic manifestation of metabolic syndrome (MetS), is common and accounts for 80% of cases of elevated liver function tests (LFTs). We assessed the long-term effects of multifactorial intervention on LFTs and their association with cardiovascular disease (CVD) events in patients with MetS without diabetes mellitus or CVD. MATERIAL AND...

Let 3E2(a1, a2, a3; b1, b2) denote the generalized hypergeometric differential equation of rank three with parameters (a1, a2, a3, b1, b2), which is defined on the projective line P(x) with reuglar singularities at x = 0, 1,∞. Any set of linearly independent solutions defines a multi-valued map from P − {0, 1,∞} to the projective plane P called the Schwarz map. The image of this map is locally ...

We have previously reported that captopril stimulates thromboxane A2 synthesis in patients with essential hypertension. In the present study, the hypotensive effects of captopril and OKY-046, a selective inhibitor of thromboxane A2 synthetase, were studied in nine patients with essential hypertension to determine whether thromboxane A2 is involved in the regulation of blood pressure. A single o...

We consider a key case in the fundamental and substantial problem of the possible Jordan canonical forms of A, B,C ∈Mn(F ) when C = AB. If A ∈ M2k(F ) (respectively B, C ∈ M2k(F ) ) is diagonalizable with two distinct eigenvalues a1, a2 (respectively b1, b2, and c1, c2), each with multiplicity k, and when C = AB, all possibilities for a1, a2, b1, b2, c1, c2 are characterized. The possibilities ...

Let {X, Y,Z,A,B, C} ∈ Q+ be such that X2 + Y 2 = A2, X2 + Z2 = B2 and Y 2 + Z2 = C2. We consider the problem of finding T ∈ Q+ such that either 1. T 2 −X2 = , T 2 − Y 2 = , T 2 − Z2 = or 2. T 2 −A2 = , T 2 − B2 = , T 2 − C2 = . We show that problem 2 always has a solution and we provide a formula for T . Extensive computation has been unable to find a single solution of problem 1.