Vesicular stomatitis virus (VSV) is an important vector-borne pathogen of bovine and equine species, causing a reportable vesicular disease. The matrix (M) protein of VSV is multifunctional and plays a key role in cytopathogenesis, apoptosis, host protein shut-off, and virion assembly/budding. Our previous findings indicated that mutations of residues flanking the (37)PSAP(40) motif within the ...

We deene and exercise the expected value of computation as a fundamental component of reeection about alternative inference strategies. We present a portion of Protos research focused on the interlacing of reeection and action under scarce resources, and discuss how the techniques have been applied in a high-stakes medical domain. The work centers on endowing a computational agent with the abil...

Abstract Purpose The purpose of this research is to study the relations between subdepression and indicators therapeutic preventive activity in patients with a previous myocardial infarction. Material methods 245 outpatient both sexes aged 35–65 years who had suffered infarction was examined. Subdepression (50–59 points on Zung scale) detected 24.0% men 41.2% women (p=0.006). As for age analysi...

Systematic modification of the 4A loop region of the Rb gene with (Py)A fluorophore units allows discrimination of the fluorescence signals corresponding to structural dynamics from single-stranded to i-motif structures.

The properties of ATM networks are explored with a special view to both the local-area and wide-area communications needs of universities and other large organisations. Scenarios for the development, deployment, and impact of ATM network in an internet environment are proposed and discussed. Particular attention is given to the impact on hub and router technology, video and voice distribution, ...

BACKGROUND The etiology and treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) remain poorly understood. Pain, lower urinary tract voiding symptoms and negative impact on quality of life (QOL) are the most common complaints. Acupuncture, which has been widely used to treat painful and chronic conditions, may be a potential treatment to alleviate the constellation of symptom...

Cellular stress can trigger a process of self-destruction known as apoptosis. Cells can also respond to stress by adaptive changes that increase their ability to tolerate normally lethal conditions. Expression of the major heat-inducible protein hsp70 protects cells from heat-induced apoptosis. hsp70 has been reported to act in some situations upstream or downstream of caspase activation, and i...

I would like to thank Andreas Nonnengart for many useful discussions and contributions, and Lincoln A. Wallen whose talk about his modal Matrix method, given in spring 1987 in Munich, inspired me to this work. Norbert Eisinger and Jörg Siekmann read drafts of this paper and gave many useful hints. and theorem provcing in first order theories with equality. 16 a world a two worlds b and c are ac...

Fovea1 and non-fovea1 after-images affect saccadic behaviour in different ways.Fovea1 after-images inhibit saccades and facilitate smooth eye movements whether or notinstructions to track the after-image are given. Parafoveal after-images are effective stimulifor eliciting consistent eye movement patterns, but these patterns change when instructions aregiven. Peripheral after-im...

Background: Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology, which characterized by erosive (synovitis) and systemic inflammation. Tofacitinib (TFCN) a small molecule Janus kinase (JAK) inhibitor that targets JAK1/JAK3. Identification patients sensitive to TFCN before treatment could significantly improve therapy outcome. Presently it not possible predict efficacy in ever...