A gene (ertX) encoding a putative ABC transporter was cloned from the erythromycin producer Saccharopolyspora erythraea, using PCR. The primers were based on regions of homology from ABC transporters which confer resistance to macrolide antibiotics. While ertX encodes a protein with a strong degree of similarity to other macrolide ABC transporters from streptomycetes and staphylococci, it did n...

This paper aims to ensure the business continuity of ABC Group by proposing a concept for changing model based on uncertainty analysis. The study suggests making changes in technology security and environmental product research development support success new designs. To continuity, project proposes following changes: diversifying greener offerings, strengthening cybersecurity measures, develop...

ABC transporters are a large family of membrane proteins that transport chemically diverse substrates across the cell membrane. Disruption mechanisms mediated by causes development various diseases, including atherosclerosis. Methods: A bioinformatic analysis dataset from Gene Expression Omnibus (GEO) was performed. GEO containing data on gene expression levels in samples atherosclerotic lesion...

pathologic fractures of the jaw are usually associated with aggressive, destructive lesions or malignant lesions of the jaws. aneurysmal bone cysts (abc) of the jaws are benign lesions which normally do not cause destruction to such an extent. this article reports a relatively aggressive abc of the mandible in a 19 year-old male which destroyed the buccal and lingual cortices as well as the inf...

Abnormal cell (ABC) is a markedly heterogeneous tissue area and can be categorized into three main types: benign hyperplasia (BH), carcinoma (Ca), and intraepithelial neoplasia (IN) or precursor cancerous lesion. In this study, the goal is to determine and characterize the continuum of colorectal cancer by using a 3D-texture approach. ABC was segmented in preprocessing step using an active cont...

OBJECTIVES This study aimed to systematically review and quantitatively synthesize the association between HLA-B*5701 and abacavir-induced hypersensitivity reaction (ABC-HSR). METHODS We searched for studies that investigated the association between HLA-B genotype and ABC-HSR and provided information about the frequency of carriers of HLA-B genotypes among cases and controls. We then performe...

Artificial Bee Colony (ABC) algorithm which is one of the most recently introduced optimization algorithms, simulates the intelligent foraging behavior of a honey bee swarm. Clustering analysis, used in many disciplines and applications, is an important tool and a descriptive task seeking to identify homogeneous groups of objects based on the values of their attributes. In this work, ABC is use...

The accumulator-based compaction (ABC) technique uses an accumulator to generate a composite fault signature for a circuit under test. The error coverage for this method has been previously analyzed using Markov chains. We describe an alternative technique for calculating the error coverage of ABC using the asymmetric error model. This technique relies on the central limit theorem of statistics...

The absorption, distribution, metabolism and excretion (ADME) of metabolites and toxic organic solutes are orchestrated by the ATP-binding cassette (ABC) transporters and the organic solute carrier family (SLC) proteins. A large number of ABC and SLC transpoters exist; however, only a small number have been well characterized. To facilitate the analysis of these transporters, which is important...