Pulchellin is a plant biotoxin categorized as type 2 ribosome-inactivating protein (RIPs) which potentially kills cells at very low concentrations. Biotoxins serve targeting immunotoxins (IT), consisting of antibodies conjugated to toxins. ITs have two independent components, human antibody and toxin with bacterial or source; therefore, they pose unique setbacks in immunogenicity. To overcome t...

Since the discovery of ricin by Kobert in 1887, considerable interest has been shown in the hemagglutinins obtainable from plants. The study of them has been somewhat overshadowed by the more recently discovered serum agglutinins, which they so remarkably resemble in action. They have, however, played an important part in immunological research throughout its history. Ricin, the extremely toxic...