A 69-year-old type 2 diabetic man was admitted due to diabetic gangrane. He had a history of subtotal gastrectomy. During hospitalization, he was treated with regular insulin and 300 mg/day of acarbose. He developed a low grade fever, cough and nasal discharge, and was given a compound "cold" remedy with anticholenergic properties. The next day, he suffered from a paralytic ileus. Oral intake a...

normal 0 false false false en-us x-none ar-sa background: high prevalence of obesity and the importance of this issue as a risk factor for chronic diseases such as severe cardiovascular diseases, diabetes, and cancer necessitate the need for treatment. the aim of this study was the evaluation of acarbose effect on the weight loss in non-diabetic overweight or obese patients in kerman. materials...

Tight control of blood glucose is the most important strategy for the treatment of diabetes mellitus. Here, we investigated the beneficial effects of Welsh onion on fasting and postprandial hyperglycemia. Inhibitory activities of hot water extracts from the green stalk and white bulb, which are the edible portions of the Welsh onion, and the fibrous root extract against yeast α-glucosidase were...

BACKGROUND/OBJECTIVES The primary objective of the treatment of diabetes mellitus is the attainment of glycemic control. Hyperglycemia increases oxidative stress which contributes to the progression of diabetic complications. Thus, the purpose of this study was to investigate the hypoglycemic and antioxidant effects of Daraesoon (Actinidia arguta shoot) in animal models of diabetes mellitus. ...

Type 2 diabetes mellitus (T2DM) is a chronic disease that poses significant global health issue. Acarbose commonly given drug to treat diabetes, which works as an inhibitor of polysaccharide-degraded enzymes. However, acarbose has side effects cause indigestion, diarrhea, flatulence, nausea, and vomiting. On the other hand, Aloe vera contains compounds have been proven antidiabetic activity by ...

AIMS/INTRODUCTION Early initiation of basal insulin therapy is recommended for normalizing fasting blood glucose in type 2 diabetes mellitus. However, basal insulin treatment might not adequately control postprandial glucose levels. The present study evaluated whether the combination of the α-glucosidase inhibitor, acarbose, and basal insulin improved blood glucose control under daily-life trea...

OBJECTIVE Acarbose and trans-chalcone are glucosidase inhibitors whose beneficial effects have been demonstrated in diabetes. The present study aimed at investigating their potential effects in obesity. MATERIALS AND METHODS NMRI male mice (n = 48) were subjected to a high fat diet for four weeks, which induced an initial state of obesity. One control group was given normal rodent diet. Obese...

A newly synthesized chromophore-modified curdlan functions as a saccharide chemosensor in aqueous solution, enabling us to discriminate tetrasaccharide acarbose from 24 mono-, di-, tri-, and tetrasaccharides.