By T. C. Willett. {Tavistock, 42s.) American research findings suggest that accident-prone drivers as a group from accident-free drivers in being significantly more often aggressive, extro^ sexually promiscuous, having a police record, and being reared in a conflict-ri1 home. These characteristics are so like those alleged to be associated with delinque'1'' that Dr. Willett was led to question ...

In the period 1987 to 1989 there were about 5,000 cases of fatal and injury-sustained road traffic accidents, of which 2.3 to 3.0% were alcohol-related (Blood alcohol levels greater than the legal limit of 80 mg % ethanol). The offenders of alcohol-related accidents are mostly Chinese (greater than 79%), predominantly of the male gender (greater than 98%), and more often than not in the 30 to 4...

Background and aims: This study aimed to investigate the deaths and injuries following pedestrian traffic accidents and factors associated with death of pedestrian in Tehran and Alborz provinces. Methods: In this cross-sectional study all traffic accidents related to pedestrians in Tehran and Alborz provinces reported from March 21, 2013 to March 21, 2014...

Accidental mechanical asphyxia is an unusual cause of death. In reviewing 73 cases occurring during a 10-year-period in Sweden, young boys and elderly women seemed to be most prone to this type of fatality. A striking number of victims had deliberately put a noose-like structure around the neck, and yet another group became entangled in some part of their clothing. Thoracic immobilization was s...

The reliable identification of beta-aggregating stretches in protein sequences is essential for the development of therapeutic agents for Alzheimer's and Parkinson's diseases, as well as other pathological conditions associated with protein deposition. Here, a model based on physicochemical properties and computational design of beta-aggregating peptide sequences is shown to be able to predict ...

OBJECTIVE The mechanisms promoting the focal formation of rupture-prone coronary plaques in vivo remain incompletely understood. This study tested the hypothesis that coronary regions exposed to low endothelial shear stress (ESS) favor subsequent development of collagen-poor, thin-capped plaques. APPROACH AND RESULTS Coronary angiography and 3-vessel intravascular ultrasound were serially per...

piratory failure may require mechanical ventilation to maintain oxygenation. Persistent hypoxemia may entail additional treatments, such as inhaled nitric oxide or high-frequency oscillation, but these treatments are not universally available. In contrast, ventilation in the prone position, first recommended in 1974, can be readily implemented in any intensive care unit (ICU), and clinicians sh...

People with epilepsy are more accident prone than the non-epilepsy population. Bone fractures are most often due to seizure-related falls. However, seizures themselves, in particular generalized tonic-clonic seizures, may also cause fractures, e.g. of the thoracic spine. Here, I present a man who developed focal epilepsy following a subarachnoidal hemorrhage. During a focal motor seizure with l...

This paper introduces a parameter-free clustering-based approach to detecting critical traffic road segments in urban areas, i.e., of spatially prolonged and high accident risk. In addition, it proposes novel domain-specific criterion for evaluating the clustering results, which promotes stability results through time inter-period spatial collocation, penalizes size selected clusters. To illust...

Translesion synthesis (TLS) employs low fidelity polymerases to replicate past damaged DNA in a potentially error-prone process. Regulatory mechanisms that prevent TLS-associated mutagenesis are unknown; however, our recent studies suggest that the PCNA-binding protein Spartan plays a role in suppression of damage-induced mutagenesis. Here, we show that Spartan negatively regulates error-prone ...