نتایج جستجو برای: acebutolol

تعداد نتایج: 162  

Journal: :Journal of pharmaceutical sciences 2009
Yukio Kato Tatsuya Miyazaki Takashi Kano Tomoko Sugiura Yoshiyuki Kubo Akira Tsuji

Gastrointestinal absorption of several beta-blockers is inhibited by citrus juices, although molecular mechanism(s) lying on their small intestinal absorption has not yet been identified. Here, we attempted to demonstrate involvement of both influx and efflux transporters in vivo in gastrointestinal absorption of celiprolol in mice. Plasma concentration of celiprolol (3 mg/kg) after oral admini...

Journal: :Journal of Molecular Liquids 2022

• Computational/experimental approaches to the binding of lysozyme with betablockers. Binding events were associated occurrence different allosteric signal propagation local perturbations. Complexes drug-protein are based on π-π interactions intervention hydrogen bounds. These results open new avenues in betablocker precision medicine and design drug-modulators. Effective reliable prediction mo...

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