We have recently synthesized [Ni (MAP) ] complex [H-MAP= 2- (methylamino) pyridine]. 2- (Methy1amino)pyridine reacts with MeLi in THF and generates the lithium salt (Li-MAP). Further reaction of NiCl with two equivalent of this ligand in THF leads to the formation of a dark red solution. Analytical data, molecular weight, and magnetic susceptibility of this complex confirm the formula [N...

Acetyl coenzyme A is an important molecule in metabolism playing role in many biochemical reactions.  Its main function is to convey the carbon atoms within the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production. In order to find out if this chemical compound could affect physiological and morphological characteristics of rosemary plant, the present study w...

Abstract Background The heterocyclic compounds particularly pyridine displayed clinical and biological implementation. Pyridine scaffolds have been detected in most relevant drug molecules that included provided a great possibility for treatment. Main text Pyridine-containing increasing importance medicinal application as antiviral, anticholinesterase activities, antimalarial, antimicrobial, an...

In the crystal structure of the title compound, [CuCl(C(5)H(5)N)(4)][N(CN)(2)]·2C(6)H(5)N, the copper(II) cations are coordinated by one chloride anion and four N-bonded pyridine ligands into discrete complexes. The copper(II) cation shows a square-pyramidal coordination environment, with the chloride anion in the apical position. However, there is one additional chloride anion at 3.0065 (9) Å,...

1. Cyanide hemochromogen probably contains one cyanide group per heme group. 2. The equilibrium between pyridine hemochromogen and its components, pyridine and reduced heme, is complicated to an unknown extent by the precipitation of reduced heme and the aggregation of pyridine hemochromogen. 3. These complications were not taken into account in R. Hill's experiments on pyridine hemochromogen. ...

amodiaquine is an antimalarial drug used in the prophylaxis and treatment of this disease. however, hepatotoxicity as a life‑threatening adverse effect is associated with its clinical use. we evaluated amodiaquine-induced toxicity in isolated rat hepatocytes as an in vitro model for studying drug‑induced hepatotoxicity. this study attempts to investigate the protective effects of taurine and n-...