acid complexes were determined. The dissociation constants of the amino acids determined are; alanine (10.29), arginine (12.02), asparagine (9.39), glycine (9.87), histidine (7.01), lysine (9.28), methionine (9.68), phenylalanine (9.61), proline (10.53), threonine (10.31), tryptophan (9.77), and valine (10.28). The ratio of metal to amino acid determined for the complexes is 1:3, except for Cu ...

Derivatives of salicylic acid (SA) and benzoic acid prevent endothelin-1 (ET-1) binding to ETA receptors. This study analyzed actions of 30 derivatives of benzoic acid and salicylic acid on (125)I-ET-1 binding to recombinant rat ETA receptors. The most active compounds were 3,5-dibromosalicylic acid (Br2SA, K(i) = 0.5 mM) and 3,5-diiodosalicylic acid (K(i) = 0.3 mM). They were about 50 times mo...

apotransferrin (apo tf)  in 0.1 m n-(2hydroxyethyl)piperazine-n2-ethanesulfanic acid at 25 ˚c  and ph 7.4 has been titrated with acidic solution of tb3+. the binding of tb3+ at  the two specific metal-binding sites of transferrin was followed from the changes in the difference uv spectra at 245 nm. the molar absorptivity per binding site for tb3+-tf is 22,500 ± 1000 m-1cm-1. to determine the tb...

the interaction of p-sulphonatocalix [6] arene towards l-arginine and l-lysine has been studied inacidic aqueous solution (p1-1 2) using uv-vis spectrophotometric titration technique. the psulphonatocalix[6] arene was found to be able to form 1:1 complexe with amino acids in water.the values of the association constant were determined at different temperatures to evaluate thethermodynamic funct...

Unsaturated long chain fatty acids are known to inhibit the binding between estrogen and estrogen receptor, or progesterone and progesterone receptor in rat uterus. The effects of long chain fatty acids on the binding between androgen receptor of castrated rat prostate and 3H-R1881 were studied. The binding was not affected by saturated fatty acids such as palmitic acid (16:0) or stearic acid (...