Acrylic cements have been used for the augmentation of weakened or partially destroyed bones for decades (1). The term vertebroplasty originally described an open surgical procedure that introduces bone graft or acrylic cement to mechanically augment weakened vertebral bodies. Polymethylmethacrylate (PMMA) is the acrylic most commonly used as a bone filler, and its application in the treatment ...

OBJECTIVE The purpose of this study is to find the optimal stiffness and volume of bone cement and their biomechanical effects on the adjacent vertebrae to determine a better strategy for conducting vertebroplasty. METHODS A three-dimensional finite-element model of a functional spinal unit was developed using computed tomography scans of a normal motion segment, comprising the T11, T12 and L...

OBJECTIVE To compare biodegradable magnesium phosphate cement (Mg-cement), calcium phosphate cement (Ca-cement), and no cement on bone repair, biocompatibility, and bone adhesive characteristics in vivo in horses. ANIMALS 8 clinically normal adult horses. PROCEDURES Triangular fragments (1-cm-long arms) were created by Y-shaped osteotomy of the second and fourth metatarsal bones (MTII and M...

head and femoral canal have usually been involved in a procedure of total hip replacement (THR). Severe complications resulting from this procedure are infrequent. However, this procedure can cause localized problems such as infection or cement leakage into the femoral vein to inferior vena cava. We report a case of symptomatic foreign body formation in the right cardiac chambers caused by acry...

OBJECTIVES The objective of this study was to determine if combining variations in mixing technique of antibiotic-impregnated polymethylmethacrylate (PMMA) cement with low frequency ultrasound (LFUS) improves antibiotic elution during the initial high phase (Phase I) and subsequent low phase (Phase II) while not diminishing mechanical strength. METHODS Three batches of vancomycin-loaded PMMA ...

Many bioactive bone cements were developed for total hip replacement and found to bond with bone directly. However, the mechanical properties at the bone/bone cement interface under load bearing are not fully understood. In this study, a bioactive bone cement, which consists of strontium-containing hydroxyapatite (Sr-HA) powder and bisphenol-alpha-glycidyl dimethacrylate (Bis-GMA)-based resin, ...

OBJECTIVE To investigate the clinical effect of high and low viscosity bone cement in vertebroplasty for treatment of osteoporotic vertebral compression fractures. METHODS 40 cases of patients with osteoporotic thoracolumbar compression fractures admitted into department of orthopeadics in our hospital were reviewed. All patients were divided into high viscosity bone cement group (20 cases) a...

Growth hormone was incorporated into Polymethylmethacrylate (PMMA) with a view to improving the quality of the bone-cement interface. Growth hormone was released from the PMMA and delivered to the cells at the bone-cement interface . The in vivo response to the growth hormone loaded cement was compared to the plain cement , using light microscopy, transmission electron microscopy and scanning e...