The simulation of the propagation of electrical activity in a realistic-geometry computer model of the ventricles of the human heart using the governing reaction-diffusion equation is described. Each model point is represented by the phase 1 LuoRudy membrane model, appropriately modified to represent human action potentials. A separate longer-duration action potential waveform was used for the ...

Nerve membranes consist of an approximately equal mixture of lipids and proteins. The propagation of nerve pulses is usually described with the ionic hypothesis, also known as the Hodgkin-Huxley model. This model assumes that proteins alone enable nerves to conduct signals due to the ability of various ion channel proteins to transport selectively sodium and potassium ions. While the ionic hypo...

In this paper, we analyze the effect of the redistribution of the transmembrane ion channels in an axon caused by longitudinal acoustic vibrations of the membrane. These oscillations can be excited by an external source of ultrasound and weak microwave radiation interacting with the charges sitting on the surface of the lipid membrane. It is shown, using the Hodgkin-Huxley model of the axon, th...

ion channels are responsible for control of cell function in excitable tissues such as heart and brain and also in organs and tissues traditionally thought to be non- excitable including liver and epithelium. in the present research, the effect of lead (pb2+) on ca2+ -dependent action potential and currents was studied in f77 neuronal soma membrane of helix aspersa. for this purpose, action pot...