BACKGROUND Both endocarditis and Bartonella infections are neglected public health problems, especially in rural Asia. Bartonella endocarditis has been described from wealthier countries in Asia, Japan, Korea, Thailand and India but there are no reports from poorer countries, such as the Lao PDR (Laos), probably because people have neglected to look. METHODOLOGY/PRINCIPAL FINDINGS We conducte...

Bacterial endocarditis is a serious medical complication of heroin addiction and should be suspected in any addict with a fever and positive blood cultures. However, gram-negative bacteria, and particularly Pseudomonas aeruginosa, are uncommon causes of bacterial endocarditis and their presence in a blood culture may be dismissed as a contaminant or as originating from another site. Therefore, ...

Infective endocarditis remains an uncommon disease thus any individual doctor's experience of it must of necessity be limited. Such patients are always "interesting" and invariably stay in hospital for weeks rather than days-this, I think, leads clinicians to assume the infection is more common than it really is. As a (clinical) microbiologist I have been in a unique position to follow all pati...

The clinical and bacteriological findings in a case of infective endocarditis caused by Kingella denitrificans are presented. This appears to be only the second report providing clear evidence for a pathogenic role for this species.

The object of this report is to record our experience with six patients in whom urgent surgical measures becaniz necessary as a result of cardiac valve destruction following bacterial endocarditis. The patients constitute a group of six in a total of 200 valve replacements and have been distinguished from three patients in whom, as a result of bacterial endocarditis, valve replacement was under...

A DESCRIPTION IS GIVEN OF TWO METHODS OF MEASURING COMBINED ANTIBIOTIC BACTERICIDAL ACTION: a test in liquid medium with subculture and the cellophane transfer method. It is emphasized that information so obtained is necessary in order to predict the effect of combined treatment, particularly in bacterial endocarditis due to organisms not fully sensitive to penicillin. Eight case histories are ...

Accurate diagnosis of infective endocarditis may be difficult. The Beth Israel criteria and the newer Duke criteria assign probability to the diagnosis of infective endocarditis on the basis of the presence of common features and manifestations. We reviewed 111 cases of pediatric infective endocarditis diagnosed and treated over 19 years. Each case was classified by the two criteria, and the re...

BACKGROUND: In March 2008, the National Institute for Health and Care Excellence recommended stopping antibiotic prophylaxis (AP) for those at risk of infective endocarditis (IE) undergoing dental procedures in the United Kingdom, citing a lack of evidence of efficacy and costeffectiveness. We have performed a new economic evaluation of AP on the basis of contemporary estimates of efficacy, adv...