OBJECTIVES Although vertebroplasty is very effective for relieving acute pain from an osteoporotic vertebral compression fracture, not all patients who undergo vertebroplasty receive the same degree of benefit from the procedure. In order to identify the ideal candidate for vertebroplasty, pre-operative prognostic demographic or clinico-radiological factors need to be identified. The objective ...

Background: The purpose of this study was to evaluate long-term changes in bone density profile among survivors of childhood acute lymphoblastic leukemia. Patients and Methods: This was a 5 year prospective study comprised of thirty-one survivors of childhood acute lymphoblastic leukemia with a mean age of 11.8 (4.6) years, who completed therapy at least 1 year previously (according to the ...

Chronic recurrent multifocal osteomyelitis (CRMO) is a form of chronic nonbacterial osteitis (CNO) characterized by one or more lytic bone lesions with no identifiable cause1. The metaphyses of long bones and the clavicle are most frequently affected, although any bone may be involved. Most cases begin in childhood, and follow an intermittent course. Pain is the most common presenting symptom. ...

BACKGROUND Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Bone pain is an important symptom that can be severe. Eosinophilia without any other abnormal laboratory findings is rare in ALL. Strongyloides stercoralis in ALL causes disseminated fatal disease. CASE PRESENTATION This 9-year-old girl presented with bone pain in lumbar region. Bone pain was the only sym...

Transient osteoporosis of the hip (TOH) is a rare disorder of unknown etiology that is characterized by acute onset of disabling bone pain. The locally increased bone turnover and low bone mineral density (BMD) associated with this disorder indicate a potential role for an antiresorptive agent such as bisphosphonate as a treatment. A previously healthy 46-year-old man developed the sudden onset...

introduction : acute lymphoblastic leukemia (all) and non-hodgkin's lymphoma (nhl) are the most common malignancies in children and adolescents. therapies such as corticosteroids, cytotoxic and radiotherapy will have harmful effect on bone mineral density (bmd) which can lead to increased possibility of osteoporosis and pathological fractures. subjects and methods: this 3-year cross-sectional s...

Figure 1. Leukemic cell morphology of bone marrow aspiration specimen (May-Grünwald-Giemsa). An 82-year-old woman was admitted to our hospital presenting with febrile neutropenia. She had been diagnosed with chronic myeloid leukemia 2 years ago and had been on imatinib treatment since [1]. A month before admission she presented with malaise, anemia, and mild leukopenia; a bone marrow aspirate a...

A 70-year-old woman with renovascular hypertension presented with 8 weeks of worsening chest pain, back and leg pain, dyspnea, and fatigue. She had a faint petechial rash on the abdomen and thighs. Complete blood count showed leukocytosis (26.6 109/L), anemia (100 g/L), and thrombocytopenia (114 109/L). Manual differential count revealed 5% myeloblasts, 2% myelocytes, 1% metamyelocytes, 1% eosi...

The clinical presentation of acute leukemia results from infiltration of bone marrow or extramedullary sites by blasts. As a result, initial symptoms may be due to the presence of anemia, neutropenia, or thrombocytopenia. Patients generally present with nonspecific complaints including weakness, lethargy, fatigue, dyspnea, fever, weight loss, or bleed‐ ing. Blasts may also infiltrate organs or ...