BACKGROUND Limited options are available for the treatment of pain in cats. Monoclonal antibodies (mAbs) that neutralize nerve growth factor (NGF) have demonstrated analgesic capacity in rodent models, people with osteoarthritis, and dogs with degenerative joint disease. HYPOTHESIS/OBJECTIVES This study describes the design and characterization of a fully felinized anti-NGF monoclonal antibod...

INTRODUCTION Monitoring whole blood anticoagulation therapy with the activated coagulation time (kaolin ACT) and the heparin management test (HMT) were correlated in vivo with the plasma anti-activated factor X (anti-Xa) heparin concentration in patients who received variable doses of aprotinin and in vitro in the presence of increasing concentrations of aprotinin. METHODS In 38 elective card...

The objective of the study is to observe the anti-motion sickness effect of volatile oil extract of Pinelia ternata in rats, compare the strength of anti-motion sickness action between the Pinelia ternata volatile oil extract and the dimenhydrinate, and analyze the constituents in volatile oil of Pinelia ternata. Rats with frequency is 0.05Hz, the peak speed of 240°/s rotated to stimulate, evok...

With new guidelines for the control of heparin infusion rates the proportion of kaolin cephalin clotting time ratios was significantly improved compared with ratios achieved without their use. Further improvement might result from careful preparation and delivery of the infusion.

Cyclizine (1-benzhydryl-4-methyl-piperazine, CAS 82-92-8, CYC, I), a piperazine derivative, belongs to H1 antihistamine group of drugs that shows such pharmacological properties as anti-inflammatory, anti-allergic and anti-platelet effects, similar to other H1-receptor antagonists. In this study, two new tolyl and cumene derivatives of I (1-ethyl-4-[(p-isopropylphenyl) (p-tolyl) methyl]-piperaz...

Assessing acidic influence in conversion of hospital plastic waste into liquid fuel with kaolin base supported catalysts was carried out using samples collected from a tertiary University teaching Hospital Sokoto, which encompassed Drip bags (Linear low density polyethylene LLDPE), Hand gloves (Polyethylene terephthalate PET) and Urine (Polyureathane PU). Uncatalyzed pyrolysis first thermal cra...

This paper presents research on the surface characteristics, specific surface area (SSA), cation exchange capacity (CEC) and the electrophoretic mobility (EPM) of kaolin clays obtained from different naturally occurring pegmatite and granite deposits worldwide. Particular emphasis was placed on studying the influence of ancillary minerals on these properties, as well as the diversity in morphol...