Angiotensinogen has been assumed to be an acute-phase protein, because some forms of acute inflammation, eg, the injection of lipopolysaccharide or cellite or partial hepatectomy, increased the hepatic synthesis of angiotensinogen. In addition, the well-characterized nephrectomy-induced stimulation of angiotensinogen was thought to represent an acute-phase reaction. To evaluate this hypothesis,...

enzootic calf bronchopneumonia is a multyfactorial disease that occurs in association whit the in telaction of various infectious agenes, and colf susceptibility. the economic losses is associated with death loss and treatment costs, reduction of live weight gain and reduced of productive life span, whith mey be considevable. the aim of this study was to examine the acute phase response in calv...

Acute phase proteins were measured in six patients before liver transplantation and for 72 h after orthotopic liver transplantation. The ability of the donor liver to mount an acute phase response was demonstrated, although the response was less than that seen in other groups of patients in whom this has been studied. Because of the reduced response to stress, the value of these measurements as...

PURPOSE The present study defines genomic loci underlying coordinate changes in gene expression following retinal injury. METHODS A group of acute phase genes expressed in diverse nervous system tissues was defined by combining microarray results from injury studies from rat retina, brain, and spinal cord. Genomic loci regulating the brain expression of acute phase genes were identified using...

Epidemiologic studies have revealed that minimal acute-phase changes predict poor prognoses in many conditions and predict disability and mortality in the elderly. These findings have usually been interpreted to indicate that inflammatory processes of some kind play a role in these situations. In fact, a minimal acute-phase response does not necessarily establish the existence of an inflammator...

Photodynamic therapy (PDT) inflicts tumor tissue injury that is experienced by the host as a local trauma. This provokes a strong host response with pronounced neutrophilia as one of its manifestations. Mouse FsaR fibrosarcoma model was used for investigating photodynamic therapy (PDT)-induced neutrophilia and its link to the acute phase response. Compared to normal mice, the extent of neutroph...

OBJECTIVE To determine the presence or absence of an acute phase response after training for court and field sports. PARTICIPANTS All members of the Australian women's soccer team (n = 18) and all members of the Australian Institute of Sport netball team (n = 14). METHODS Twelve acute phase reactants (white blood cell count, neutrophil count, platelet count, serum iron, ferritin, and transf...

During the acute phase response to tissue injury or inflammation, the concentration of several plasma proteins change. Previous work (29-34) suggested a role for interleukin 1 (IL-1) in the acute phase response. The availability of recombinant-generated mouse IL-1 prompted a study designed to directly test the function of IL-1 and its mechanism of action on hepatic synthesis of two positive acu...

Exogenous interleukin 6 (IL-6), synthesized at the initiation of the acute phase response, is considered responsible for signaling hepatocytes to produce acute phase proteins. It is widely posited that IL-6 is either delivered to the liver in an endocrine fashion from immune cells at the site of injury, or alternatively, in a paracrine manner by hepatic immune cells within the liver. A recent p...

introduction: evaluating patient with acute scrotum is based on medical history (e.g. age), physical examination, blood tests, urine analysis and imaging studies. differential diagnosis may be difficult. efficacy of serum acute phase proteins in patients with acute scrotum was assessed in this study. materials and methods : 45 patients were recruited and allocated within three sub-groups; acute...