نتایج جستجو برای: acute thrombocytopenia

تعداد نتایج: 516851  

Journal: :Blood 2011
Patrizia Noris Silverio Perrotta Marco Seri Alessandro Pecci Chiara Gnan Giuseppe Loffredo Nuria Pujol-Moix Marco Zecca Francesca Scognamiglio Daniela De Rocco Francesca Punzo Federica Melazzini Saverio Scianguetta Maddalena Casale Caterina Marconi Tommaso Pippucci Giovanni Amendola Lucia D Notarangelo Catherine Klersy Elisa Civaschi Carlo L Balduini Anna Savoia

Until recently, thrombocytopenia 2 (THC2) was considered an exceedingly rare form of autosomal dominant thrombocytopenia and only 2 families were known. However, we recently identified mutations in the 5'-untranslated region of the ANKRD26 gene in 9 THC2 families. Here we report on 12 additional pedigrees with ANKRD26 mutations, 6 of which are new. Because THC2 affected 21 of the 210 families i...

Journal: :Journal of Ayub Medical College, Abbottabad : JAMC 2009
Shuaib Ansari Haji Khan Khoharo Allauddin Abro Israr Ahmd Akhund Fatima Qureshi

BACKGROUND Malaria is usually associated with reduced blood cell counts & mild to moderate thrombocytopenia is a common association of malaria. The cause of thrombocytopenia is poorly understood, but the immune-mediated lysis, sequestration in the spleen and dyspoietic processes in the marrow with diminished platelet production have all been postulated. This study was conducted to evaluate thro...

Journal: :Stroke 2007
Brett L Cucchiara Bryon Jackson Mark Weiner Steven R Messe

BACKGROUND AND PURPOSE Thrombolysis for acute ischemic stroke is strikingly time sensitive. Current guidelines require confirmation of a platelet count > or =100,000 before thrombolysis; however, obtaining this laboratory test may delay treatment. METHODS We queried our hospital database to identify patients with ICD-9 codes consistent with acute ischemic stroke from 2000 to 2005 and to deter...

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